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Enhanced Metabolome Coverage and Evaluation of Matrix Effects by the Use of Experimental-Condition-Matched (13)C-Labeled Biological Samples in Isotope-Assisted LC-HRMS Metabolomics

Stable isotope-assisted approaches can improve untargeted liquid chromatography-high resolution mass spectrometry (LC-HRMS) metabolomics studies. Here, we demonstrate at the example of chemically stressed wheat that metabolome-wide internal standardization by globally (13)C-labeled metabolite extrac...

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Detalles Bibliográficos
Autores principales:	Ćeranić, Asja, Bueschl, Christoph, Doppler, Maria, Parich, Alexandra, Xu, Kangkang, Lemmens, Marc, Buerstmayr, Hermann, Schuhmacher, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692853/ https://www.ncbi.nlm.nih.gov/pubmed/33121096 http://dx.doi.org/10.3390/metabo10110434

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