Diversely Functionalised Cytochalasins through Mutasynthesis and Semi‐Synthesis

Mutasynthesis of pyrichalasin H from Magnaporthe grisea NI980 yielded a series of unprecedented 4′‐substituted cytochalasin analogues in titres as high as the wild‐type system (≈60 mg L(−1)). Halogenated, O‐alkyl, O‐allyl and O‐propargyl examples were formed, as well as a 4′‐azido analogue. 4′‐O‐Pro...

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Detalles Bibliográficos
Autores principales: Wang, Chongqing, Lambert, Christopher, Hauser, Maurice, Deuschmann, Adrian, Zeilinger, Carsten, Rottner, Klemens, Stradal, Theresia E. B., Stadler, Marc, Skellam, Elizabeth J., Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692911/
https://www.ncbi.nlm.nih.gov/pubmed/32484589
http://dx.doi.org/10.1002/chem.202002241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692911/
https://www.ncbi.nlm.nih.gov/pubmed/32484589
http://dx.doi.org/10.1002/chem.202002241

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