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Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI

Dental anomalies coincide with genetic disorders, and prenatal identification may contribute to a more accurate diagnosis. The aim of this study was to assess whether fetal Magnet Resonance Imaging (MRI) is suitable to visualize and investigate intrauterine dental development in the upper jaw, and t...

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Autores principales: Kunzendorf, Burkhard, Diogo, Mariana C., Covini, Delfina I., Weber, Michael, Gruber, Gerlinde M., Zeilhofer, Hans-Florian, Berg, Britt-Isabelle, Prayer, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693030/
https://www.ncbi.nlm.nih.gov/pubmed/33114485
http://dx.doi.org/10.3390/jcm9113424
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author Kunzendorf, Burkhard
Diogo, Mariana C.
Covini, Delfina I.
Weber, Michael
Gruber, Gerlinde M.
Zeilhofer, Hans-Florian
Berg, Britt-Isabelle
Prayer, Daniela
author_facet Kunzendorf, Burkhard
Diogo, Mariana C.
Covini, Delfina I.
Weber, Michael
Gruber, Gerlinde M.
Zeilhofer, Hans-Florian
Berg, Britt-Isabelle
Prayer, Daniela
author_sort Kunzendorf, Burkhard
collection PubMed
description Dental anomalies coincide with genetic disorders, and prenatal identification may contribute to a more accurate diagnosis. The aim of this study was to assess whether fetal Magnet Resonance Imaging (MRI) is suitable to visualize and investigate intrauterine dental development in the upper jaw, and to compare the quality of visibility of tooth buds between 1.5 Tesla (T) and 3T images. MR images of fetuses Gestational Week (GW) 26.71 ± 4.97 from 286 pregnant women with diagnoses unrelated to dental anomalies were assessed by three raters. We compared the visibility between groups and field strengths in five gestational age groups, using chi square and Fisher’s exact tests. All ten primary tooth buds were identifiable in 5.4% at GW 18–21, in 75.5% at GW 26–29, and in 90.6% at GW 34+. Before GW 30, more tooth buds were identifiable on 3T images than on 1.5T images. Statistical significance was only reached for identification of incisors (p = 0.047). Therefore, 1.5T and 3T images are viable to visualize tooth buds, particularly after GW 25, and their analysis may serve as diagnostic criterion. MRI tooth bud data might have an impact on various fields of research, such as the maldevelopment of teeth and their causes. Analyzing tooth buds as an additional diagnostic criterion is not time consuming, and could lead to an improvement of syndrome diagnosis.
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spelling pubmed-76930302020-11-28 Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI Kunzendorf, Burkhard Diogo, Mariana C. Covini, Delfina I. Weber, Michael Gruber, Gerlinde M. Zeilhofer, Hans-Florian Berg, Britt-Isabelle Prayer, Daniela J Clin Med Article Dental anomalies coincide with genetic disorders, and prenatal identification may contribute to a more accurate diagnosis. The aim of this study was to assess whether fetal Magnet Resonance Imaging (MRI) is suitable to visualize and investigate intrauterine dental development in the upper jaw, and to compare the quality of visibility of tooth buds between 1.5 Tesla (T) and 3T images. MR images of fetuses Gestational Week (GW) 26.71 ± 4.97 from 286 pregnant women with diagnoses unrelated to dental anomalies were assessed by three raters. We compared the visibility between groups and field strengths in five gestational age groups, using chi square and Fisher’s exact tests. All ten primary tooth buds were identifiable in 5.4% at GW 18–21, in 75.5% at GW 26–29, and in 90.6% at GW 34+. Before GW 30, more tooth buds were identifiable on 3T images than on 1.5T images. Statistical significance was only reached for identification of incisors (p = 0.047). Therefore, 1.5T and 3T images are viable to visualize tooth buds, particularly after GW 25, and their analysis may serve as diagnostic criterion. MRI tooth bud data might have an impact on various fields of research, such as the maldevelopment of teeth and their causes. Analyzing tooth buds as an additional diagnostic criterion is not time consuming, and could lead to an improvement of syndrome diagnosis. MDPI 2020-10-26 /pmc/articles/PMC7693030/ /pubmed/33114485 http://dx.doi.org/10.3390/jcm9113424 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kunzendorf, Burkhard
Diogo, Mariana C.
Covini, Delfina I.
Weber, Michael
Gruber, Gerlinde M.
Zeilhofer, Hans-Florian
Berg, Britt-Isabelle
Prayer, Daniela
Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI
title Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI
title_full Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI
title_fullStr Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI
title_full_unstemmed Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI
title_short Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI
title_sort comparison of the visibility of fetal tooth buds on 1.5 and 3 tesla mri
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693030/
https://www.ncbi.nlm.nih.gov/pubmed/33114485
http://dx.doi.org/10.3390/jcm9113424
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