Identification of Amino Acid Residues Responsible for C−H Activation in Type‐III Copper Enzymes by Generating Tyrosinase Activity in a Catechol Oxidase

Tyrosinases (TYRs) catalyze the hydroxylation of phenols and the oxidation of the resulting o‐diphenols to o‐quinones, while catechol oxidases (COs) exhibit only the latter activity. Aurone synthase (AUS) is not able to react with classical tyrosinase substrates, such as tyramine and l‐tyrosine, whi...

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Detalles Bibliográficos
Autores principales: Kampatsikas, Ioannis, Pretzler, Matthias, Rompel, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693034/
https://www.ncbi.nlm.nih.gov/pubmed/32701181
http://dx.doi.org/10.1002/anie.202008859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693034/
https://www.ncbi.nlm.nih.gov/pubmed/32701181
http://dx.doi.org/10.1002/anie.202008859

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