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Identification of Amino Acid Residues Responsible for C−H Activation in Type‐III Copper Enzymes by Generating Tyrosinase Activity in a Catechol Oxidase
Tyrosinases (TYRs) catalyze the hydroxylation of phenols and the oxidation of the resulting o‐diphenols to o‐quinones, while catechol oxidases (COs) exhibit only the latter activity. Aurone synthase (AUS) is not able to react with classical tyrosinase substrates, such as tyramine and l‐tyrosine, whi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693034/ https://www.ncbi.nlm.nih.gov/pubmed/32701181 http://dx.doi.org/10.1002/anie.202008859 |