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Acid Sphingomyelinase Contributes to the Control of Mycobacterial Infection via a Signaling Cascade Leading from Reactive Oxygen Species to Cathepsin D

Tuberculosis, caused by Mycobacterium tuberculosis, is one of the most severe diseases worldwide. The initial pulmonary localization of the pathogen often develops into systemic infection with high lethality. The present work investigated the role of sphingolipids, specifically the function of acid...

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Detalles Bibliográficos
Autores principales:	Wu, Yuqing, Li, Cao, Peng, Huiming, Swaidan, Ashraf, Riehle, Andrea, Pollmeier, Barbara, Zhang, Yang, Gulbins, Erich, Grassmé, Heike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693114/ https://www.ncbi.nlm.nih.gov/pubmed/33153072 http://dx.doi.org/10.3390/cells9112406

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