Cargando…

Metformin inhibits epithelial-mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF-1α/PKM2/STAT3 pathway

Epithelial-mesenchymal transition (EMT) serves an important role in the formation and development of various types of cancer, including oral squamous cell carcinoma (OSCC). Metformin, used for treating type 2 diabetes, has been revealed to exert an anticancer effect in various types of cancer, inclu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Weihuang, Liu, Yang, Liu, Xinchen, Ma, Xiaozhou, Sun, Bin, Yu, Ziying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693125/
https://www.ncbi.nlm.nih.gov/pubmed/33262823
http://dx.doi.org/10.3892/ol.2020.12292