Cargando…
Interleukin‐6‐mediated resistance to immunotherapy is linked to impaired myeloid cell function
High serum levels of interleukin‐6 (IL‐6) correlate with poor prognosis and chemotherapy resistance in several cancers. The underlying mechanisms and its effects on immunotherapy are largely unknown. To address this, we developed a human papillomavirus type 16 (HPV16)‐associated tumor model expressi...
Autores principales: | Beyranvand Nejad, Elham, Labrie, Camilla, van der Sluis, Tetje C., van Duikeren, Suzanne, Franken, Kees L. M. C., Roosenhoff, Rueshandra, Arens, Ramon, van Hall, Thorbald, van der Burg, Sjoerd H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693233/ https://www.ncbi.nlm.nih.gov/pubmed/32875568 http://dx.doi.org/10.1002/ijc.33280 |
Ejemplares similares
-
Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy
por: Beyranvand Nejad, Elham, et al.
Publicado: (2020) -
IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors
por: Beyranvand Nejad, Elham, et al.
Publicado: (2021) -
NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division
por: Borst, Linda, et al.
Publicado: (2021) -
A pre‐existing coordinated inflammatory microenvironment is associated with complete response of vulvar high‐grade squamous intraepithelial lesions to different forms of immunotherapy
por: Abdulrahman, Ziena, et al.
Publicado: (2020) -
Delayed vaccine-induced CD8(+) T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication
por: van der Sluis, Tetje C, et al.
Publicado: (2023)