TRPM2 promotes autophagic degradation in vascular smooth muscle cells

Transient receptor potential channel M2 (TRPM2) is a Ca(2+)-permeable channel that is activated by reactive oxygen species (ROS). In many cell types, ROS activate TRPM2 to induce excessive Ca(2+) influx, resulting in Ca(2+) overload and consequent cell death. Recent studies suggest that TRPM2 may al...

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Detalles Bibliográficos
Autores principales: Zhao, Qiannan, Li, Jingxuan, Ko, Wing-Hung, Kwan, Yiu-Wa, Jiang, Liwen, Sun, Lei, Yao, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693237/
https://www.ncbi.nlm.nih.gov/pubmed/33244095
http://dx.doi.org/10.1038/s41598-020-77620-y

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