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Antagonistic effects of activin A and TNF-α on the activation of L929 fibroblast cells via Smad3-independent signaling
Fibroblasts play an important role in inflammation and tissue fibrosis. Both activin A and TNF-α can activate immune cells, however, the roles and relationship of them in activating fibroblasts in inflammation remain unclear. Here, this study revealed that TNF-α promoted the release of NO and IL-6 b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693280/ https://www.ncbi.nlm.nih.gov/pubmed/33244088 http://dx.doi.org/10.1038/s41598-020-77783-8 |