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Transcriptional Control of Regulatory T Cells in Cancer: Toward Therapeutic Targeting?

SIMPLE SUMMARY: Cancer outcomes are often indexed to the quality of the immune response to the tumor. Among immune cells, Foxp3(+) regulatory T cells (Treg cells) are potent inhibitors of cancer immunity, and their presence within solid tumors is generally associated with a poor prognosis. Thus, und...

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Detalles Bibliográficos
Autores principales: Stéphan, Pierre, Lautraite, Raphaëlle, Voisin, Allison, Grinberg-Bleyer, Yenkel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693300/
https://www.ncbi.nlm.nih.gov/pubmed/33143070
http://dx.doi.org/10.3390/cancers12113194