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Identification of Novel Mutations and Expressions of EPAS1 in Phaeochromocytomas and Paragangliomas
Endothelial PAS domain-containing protein 1 (EPAS1) is an oxygen-sensitive component of the hypoxia-inducible factors (HIFs) having reported implications in many cancers by inducing a pseudo-hypoxic microenvironment. However, the molecular dysregulation and clinical significance of EPAS1 has never b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693385/ https://www.ncbi.nlm.nih.gov/pubmed/33114456 http://dx.doi.org/10.3390/genes11111254 |