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High frequency of microsatellite instability and its substantial co-existence with KRAS and BRAF mutations in Vietnamese patients with colorectal cancer
Tumor heterogeneity and resistance to chemotherapy have been recognized as two major obstacles in the diagnosis and treatment of colorectal cancer (CRC). Microsatellite instability (MSI) and KRAS and BRAF mutations are common diagnostic factors that have been widely used to classify CRC for therapeu...
Autores principales: | Nguyen, Ha Thi, Le, Do Thanh, Duong, Quan Hong, Tatipamula, Vinay Bharadwaj, Van Nguyen, Bang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693389/ https://www.ncbi.nlm.nih.gov/pubmed/33262833 http://dx.doi.org/10.3892/ol.2020.12302 |
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