ROS Overproduction Sensitises Myeloma Cells to Bortezomib-Induced Apoptosis and Alleviates Tumour Microenvironment-Mediated Cell Resistance

Multiple myeloma (MM) is a plasma cell neoplasm that remains incurable due to innate or acquired resistance. Although MM cells produce high intracellular levels of reactive oxygen species (ROS), we hypothesised that they could remain sensitive to ROS unbalance. We tested if the inhibition of ROS, on...

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Detalles Bibliográficos
Autores principales: Caillot, Mélody, Zylbersztejn, Florence, Maitre, Elsa, Bourgeais, Jérôme, Hérault, Olivier, Sola, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693395/
https://www.ncbi.nlm.nih.gov/pubmed/33114738
http://dx.doi.org/10.3390/cells9112357

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