An Overview of the Ferroptosis Hallmarks in Friedreich’s Ataxia

Background: Friedreich’s ataxia (FRDA) is a neurodegenerative disease characterized by early mortality due to hypertrophic cardiomyopathy. FRDA is caused by reduced levels of frataxin (FXN), a mitochondrial protein involved in the synthesis of iron-sulphur clusters, leading to iron accumulation at t...

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Detalles Bibliográficos
Autores principales: Turchi, Riccardo, Faraonio, Raffaella, Lettieri-Barbato, Daniele, Aquilano, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693407/
https://www.ncbi.nlm.nih.gov/pubmed/33126466
http://dx.doi.org/10.3390/biom10111489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693407/
https://www.ncbi.nlm.nih.gov/pubmed/33126466
http://dx.doi.org/10.3390/biom10111489

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