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CDKN2A and MTAP Are Useful Biomarkers Detectable by Droplet Digital PCR in Malignant Pleural Mesothelioma: A Potential Alternative Method in Diagnosis Compared to Fluorescence In Situ Hybridisation

BACKGROUND: The diagnosis of malignant pleural mesothelioma (MPM) can be difficult, in part due to the difficulty in distinguishing between MPM and reactive mesothelial hyperplasia (RMH). The tumor suppressor gene, CDKN2A, is frequently silenced by epigenetic mechanisms in many cancers; in the case...

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Detalles Bibliográficos
Autores principales:	Cheng, Yuen Yee, Yuen, Man Lee, Rath, Emma M., Johnson, Ben, Zhuang, Ling, Yu, Ta-kun, Aleksova, Vesna, Linton, Anthony, Kao, Steven, Clarke, Candice Julie, McCaughan, Brian C., Takahashi, Ken, Lee, Kenneth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693432/ https://www.ncbi.nlm.nih.gov/pubmed/33304846 http://dx.doi.org/10.3389/fonc.2020.579327

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