Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2

Human amnion-derived mesenchymal stem cells (AD-MSCs) have been reported as a promising effective treatment to repair tissue. Trophoblast dysfunction during pregnancy is significantly involved in the pathogenesis of preeclampsia (PE). To understand how AD-MSCs regulated trophoblast function, we trea...

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Detalles Bibliográficos
Autores principales: Chu, Yijing, Chen, Weiping, Peng, Wei, Liu, Yong, Xu, Lin, Zuo, Jianxin, Zhou, Jun, Zhang, Yan, Zhang, Ning, Li, Jing, Liu, Ling, Yao, Ke, Gao, Guoqiang, Wang, Xiaofei, Han, Rendong, Liu, Chong, Li, Yan, Zhou, Huansheng, Huang, Yuxiang, Ye, Yuanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693549/
https://www.ncbi.nlm.nih.gov/pubmed/33304896
http://dx.doi.org/10.3389/fcell.2020.545852

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