RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status

SIMPLE SUMMARY: PTEN is an important tumor suppressor that is frequently mutated in malignancy. PTEN mutational loss has been associated with reduced RAD51 expression and homologous recombination deficiency (HRD), however; recent studies have failed to recapitulate these findings. Here, we show that...

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Detalles Bibliográficos
Autores principales: Sinha, Asha, Saleh, Ali, Endersby, Raelene, Yuan, Shek H., Chokshi, Chirayu R., Brown, Kevin R., Kuzio, Bozena, Kauppinen, Tiina, Singh, Sheila K., Baker, Suzanne J., McKinnon, Peter J., Katyal, Sachin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693555/
https://www.ncbi.nlm.nih.gov/pubmed/33138032
http://dx.doi.org/10.3390/cancers12113178

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