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Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis

SARS-CoV-2 led to considerable morbidity/mortality worldwide and tremendously impacted on daily life. Strict lockdown measures were implemented early to contain the viral outbreak in Austria. Massive changes in organizational structures of healthcare facilities followed with unclear implications on...

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Autores principales: Watschinger, Bruno, Watschinger, Clara, Reindl-Schwaighofer, Roman, Meyer, Elias L., Deak, Andras T., Hammer, Tamara, Eigner, Manfred, Sprenger-Mähr, Hannelore, Schneeberger, Stefan, Cejka, Daniel, Mayer, Gert, Oberbauer, Rainer, Rosenkranz, Alexander R., Kerschbaum, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693584/
https://www.ncbi.nlm.nih.gov/pubmed/33126481
http://dx.doi.org/10.3390/jcm9113465
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author Watschinger, Bruno
Watschinger, Clara
Reindl-Schwaighofer, Roman
Meyer, Elias L.
Deak, Andras T.
Hammer, Tamara
Eigner, Manfred
Sprenger-Mähr, Hannelore
Schneeberger, Stefan
Cejka, Daniel
Mayer, Gert
Oberbauer, Rainer
Rosenkranz, Alexander R.
Kerschbaum, Julia
author_facet Watschinger, Bruno
Watschinger, Clara
Reindl-Schwaighofer, Roman
Meyer, Elias L.
Deak, Andras T.
Hammer, Tamara
Eigner, Manfred
Sprenger-Mähr, Hannelore
Schneeberger, Stefan
Cejka, Daniel
Mayer, Gert
Oberbauer, Rainer
Rosenkranz, Alexander R.
Kerschbaum, Julia
author_sort Watschinger, Bruno
collection PubMed
description SARS-CoV-2 led to considerable morbidity/mortality worldwide and tremendously impacted on daily life. Strict lockdown measures were implemented early to contain the viral outbreak in Austria. Massive changes in organizational structures of healthcare facilities followed with unclear implications on the care of non-COVID-19-affected patients. We studied the nationwide impact of COVID-19 on kidney transplantation in Austria during the first six months of 2020. Concurrent with general lockdown measures, all kidney transplant activity was suspended from 13 March to 9 April. Nevertheless, between January and June, total transplant (p = 0.48) and procured donor organ numbers (p = 0.6) did not differ significantly from earlier years. Ten (0.18%) of 5512 prevalent Austrian kidney transplant recipients were diagnosed with SARS-CoV-2. The case fatality rate (one death; 10%) in renal transplant patients was less than in other countries but higher than in Austria’s general population (2.4%). We conclude that early and strict general lockdown measures imposed by the government allowed an early, however cautious, re-opening of Austrian transplant programs and played a crucial role for the favorable outcomes of SARS-CoV-2 in Austrian kidney transplant patients. Even though it may be uncertain whether similar results may be obtainable in other countries, the findings may support early intervention strategies during similar episodes in the future.
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spelling pubmed-76935842020-11-28 Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis Watschinger, Bruno Watschinger, Clara Reindl-Schwaighofer, Roman Meyer, Elias L. Deak, Andras T. Hammer, Tamara Eigner, Manfred Sprenger-Mähr, Hannelore Schneeberger, Stefan Cejka, Daniel Mayer, Gert Oberbauer, Rainer Rosenkranz, Alexander R. Kerschbaum, Julia J Clin Med Article SARS-CoV-2 led to considerable morbidity/mortality worldwide and tremendously impacted on daily life. Strict lockdown measures were implemented early to contain the viral outbreak in Austria. Massive changes in organizational structures of healthcare facilities followed with unclear implications on the care of non-COVID-19-affected patients. We studied the nationwide impact of COVID-19 on kidney transplantation in Austria during the first six months of 2020. Concurrent with general lockdown measures, all kidney transplant activity was suspended from 13 March to 9 April. Nevertheless, between January and June, total transplant (p = 0.48) and procured donor organ numbers (p = 0.6) did not differ significantly from earlier years. Ten (0.18%) of 5512 prevalent Austrian kidney transplant recipients were diagnosed with SARS-CoV-2. The case fatality rate (one death; 10%) in renal transplant patients was less than in other countries but higher than in Austria’s general population (2.4%). We conclude that early and strict general lockdown measures imposed by the government allowed an early, however cautious, re-opening of Austrian transplant programs and played a crucial role for the favorable outcomes of SARS-CoV-2 in Austrian kidney transplant patients. Even though it may be uncertain whether similar results may be obtainable in other countries, the findings may support early intervention strategies during similar episodes in the future. MDPI 2020-10-28 /pmc/articles/PMC7693584/ /pubmed/33126481 http://dx.doi.org/10.3390/jcm9113465 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Watschinger, Bruno
Watschinger, Clara
Reindl-Schwaighofer, Roman
Meyer, Elias L.
Deak, Andras T.
Hammer, Tamara
Eigner, Manfred
Sprenger-Mähr, Hannelore
Schneeberger, Stefan
Cejka, Daniel
Mayer, Gert
Oberbauer, Rainer
Rosenkranz, Alexander R.
Kerschbaum, Julia
Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
title Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
title_full Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
title_fullStr Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
title_full_unstemmed Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
title_short Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
title_sort impact of timely public health measures on kidney transplantation in austria during the sars-cov-2 outbreak—a nationwide analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693584/
https://www.ncbi.nlm.nih.gov/pubmed/33126481
http://dx.doi.org/10.3390/jcm9113465
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