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Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
Purpose: The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is currently unknown in this group. Methods: Sixty-nine patients met the Fukuda...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693605/ https://www.ncbi.nlm.nih.gov/pubmed/33114704 http://dx.doi.org/10.3390/jcm9113436 |
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author | Kujawski, Sławomir Cossington, Jo Słomko, Joanna Dawes, Helen Strong, James W.L. Estevez-Lopez, Fernando Murovska, Modra Newton, Julia L. Hodges, Lynette Zalewski, Paweł |
author_facet | Kujawski, Sławomir Cossington, Jo Słomko, Joanna Dawes, Helen Strong, James W.L. Estevez-Lopez, Fernando Murovska, Modra Newton, Julia L. Hodges, Lynette Zalewski, Paweł |
author_sort | Kujawski, Sławomir |
collection | PubMed |
description | Purpose: The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is currently unknown in this group. Methods: Sixty-nine patients met the Fukuda criteria. Patients completed baseline measures assessing fatigue, autonomic nervous system (ANS), cognitive, and cardiovascular function. Thirty-four patients completed a home-based SEP consisting of 10–40 min per day at between 30 and 80% actual HR max. Exercise intensity and time was increased gradually across the 16 weeks and baseline measures were repeated following the SEP. Results: Thirty-five patients discontinued, while 34 completed SEP. For every increase in sympathetic drive for blood pressure control as measured by the taskforce, completion of SEP decreased by a multiple of 0.1. For a 1 millisecond increase in reaction time for the simple reaction time (SRT), the probability for completion of SEP also decreases by a multiple of 0.01. For a one beat HRmax increase, there is a 4% increase in the odds of completing SEP. Conclusion: The more sympathetic drive in the control of blood vessels, the longer the reaction time on simple visual stimuli and the lower the HRmax during physical exercise, then the lower the chance of SEP completion in ME/CFS. |
format | Online Article Text |
id | pubmed-7693605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76936052020-11-28 Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients Kujawski, Sławomir Cossington, Jo Słomko, Joanna Dawes, Helen Strong, James W.L. Estevez-Lopez, Fernando Murovska, Modra Newton, Julia L. Hodges, Lynette Zalewski, Paweł J Clin Med Article Purpose: The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is currently unknown in this group. Methods: Sixty-nine patients met the Fukuda criteria. Patients completed baseline measures assessing fatigue, autonomic nervous system (ANS), cognitive, and cardiovascular function. Thirty-four patients completed a home-based SEP consisting of 10–40 min per day at between 30 and 80% actual HR max. Exercise intensity and time was increased gradually across the 16 weeks and baseline measures were repeated following the SEP. Results: Thirty-five patients discontinued, while 34 completed SEP. For every increase in sympathetic drive for blood pressure control as measured by the taskforce, completion of SEP decreased by a multiple of 0.1. For a 1 millisecond increase in reaction time for the simple reaction time (SRT), the probability for completion of SEP also decreases by a multiple of 0.01. For a one beat HRmax increase, there is a 4% increase in the odds of completing SEP. Conclusion: The more sympathetic drive in the control of blood vessels, the longer the reaction time on simple visual stimuli and the lower the HRmax during physical exercise, then the lower the chance of SEP completion in ME/CFS. MDPI 2020-10-26 /pmc/articles/PMC7693605/ /pubmed/33114704 http://dx.doi.org/10.3390/jcm9113436 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kujawski, Sławomir Cossington, Jo Słomko, Joanna Dawes, Helen Strong, James W.L. Estevez-Lopez, Fernando Murovska, Modra Newton, Julia L. Hodges, Lynette Zalewski, Paweł Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients |
title | Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients |
title_full | Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients |
title_fullStr | Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients |
title_full_unstemmed | Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients |
title_short | Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients |
title_sort | prediction of discontinuation of structured exercise programme in chronic fatigue syndrome patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693605/ https://www.ncbi.nlm.nih.gov/pubmed/33114704 http://dx.doi.org/10.3390/jcm9113436 |
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