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Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients

Purpose: The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is currently unknown in this group. Methods: Sixty-nine patients met the Fukuda...

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Autores principales: Kujawski, Sławomir, Cossington, Jo, Słomko, Joanna, Dawes, Helen, Strong, James W.L., Estevez-Lopez, Fernando, Murovska, Modra, Newton, Julia L., Hodges, Lynette, Zalewski, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693605/
https://www.ncbi.nlm.nih.gov/pubmed/33114704
http://dx.doi.org/10.3390/jcm9113436
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author Kujawski, Sławomir
Cossington, Jo
Słomko, Joanna
Dawes, Helen
Strong, James W.L.
Estevez-Lopez, Fernando
Murovska, Modra
Newton, Julia L.
Hodges, Lynette
Zalewski, Paweł
author_facet Kujawski, Sławomir
Cossington, Jo
Słomko, Joanna
Dawes, Helen
Strong, James W.L.
Estevez-Lopez, Fernando
Murovska, Modra
Newton, Julia L.
Hodges, Lynette
Zalewski, Paweł
author_sort Kujawski, Sławomir
collection PubMed
description Purpose: The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is currently unknown in this group. Methods: Sixty-nine patients met the Fukuda criteria. Patients completed baseline measures assessing fatigue, autonomic nervous system (ANS), cognitive, and cardiovascular function. Thirty-four patients completed a home-based SEP consisting of 10–40 min per day at between 30 and 80% actual HR max. Exercise intensity and time was increased gradually across the 16 weeks and baseline measures were repeated following the SEP. Results: Thirty-five patients discontinued, while 34 completed SEP. For every increase in sympathetic drive for blood pressure control as measured by the taskforce, completion of SEP decreased by a multiple of 0.1. For a 1 millisecond increase in reaction time for the simple reaction time (SRT), the probability for completion of SEP also decreases by a multiple of 0.01. For a one beat HRmax increase, there is a 4% increase in the odds of completing SEP. Conclusion: The more sympathetic drive in the control of blood vessels, the longer the reaction time on simple visual stimuli and the lower the HRmax during physical exercise, then the lower the chance of SEP completion in ME/CFS.
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spelling pubmed-76936052020-11-28 Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients Kujawski, Sławomir Cossington, Jo Słomko, Joanna Dawes, Helen Strong, James W.L. Estevez-Lopez, Fernando Murovska, Modra Newton, Julia L. Hodges, Lynette Zalewski, Paweł J Clin Med Article Purpose: The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is currently unknown in this group. Methods: Sixty-nine patients met the Fukuda criteria. Patients completed baseline measures assessing fatigue, autonomic nervous system (ANS), cognitive, and cardiovascular function. Thirty-four patients completed a home-based SEP consisting of 10–40 min per day at between 30 and 80% actual HR max. Exercise intensity and time was increased gradually across the 16 weeks and baseline measures were repeated following the SEP. Results: Thirty-five patients discontinued, while 34 completed SEP. For every increase in sympathetic drive for blood pressure control as measured by the taskforce, completion of SEP decreased by a multiple of 0.1. For a 1 millisecond increase in reaction time for the simple reaction time (SRT), the probability for completion of SEP also decreases by a multiple of 0.01. For a one beat HRmax increase, there is a 4% increase in the odds of completing SEP. Conclusion: The more sympathetic drive in the control of blood vessels, the longer the reaction time on simple visual stimuli and the lower the HRmax during physical exercise, then the lower the chance of SEP completion in ME/CFS. MDPI 2020-10-26 /pmc/articles/PMC7693605/ /pubmed/33114704 http://dx.doi.org/10.3390/jcm9113436 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kujawski, Sławomir
Cossington, Jo
Słomko, Joanna
Dawes, Helen
Strong, James W.L.
Estevez-Lopez, Fernando
Murovska, Modra
Newton, Julia L.
Hodges, Lynette
Zalewski, Paweł
Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
title Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
title_full Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
title_fullStr Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
title_full_unstemmed Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
title_short Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
title_sort prediction of discontinuation of structured exercise programme in chronic fatigue syndrome patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693605/
https://www.ncbi.nlm.nih.gov/pubmed/33114704
http://dx.doi.org/10.3390/jcm9113436
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