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Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study

Esophagectomies are among the most invasive surgical procedures that highly influence health-related quality of life (HRQoL). Recent improvements have helped to achieve longer survival. Therefore, long-term postoperative HRQoL needs to be emphasized in addition to classic criterions like morbidity a...

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Autores principales: Mehdorn, Anne-Sophie, Möller, Thorben, Franke, Frederike, Richter, Florian, Kersebaum, Jan-Niclas, Becker, Thomas, Egberts, Jan-Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693702/
https://www.ncbi.nlm.nih.gov/pubmed/33142987
http://dx.doi.org/10.3390/jcm9113513
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author Mehdorn, Anne-Sophie
Möller, Thorben
Franke, Frederike
Richter, Florian
Kersebaum, Jan-Niclas
Becker, Thomas
Egberts, Jan-Hendrik
author_facet Mehdorn, Anne-Sophie
Möller, Thorben
Franke, Frederike
Richter, Florian
Kersebaum, Jan-Niclas
Becker, Thomas
Egberts, Jan-Hendrik
author_sort Mehdorn, Anne-Sophie
collection PubMed
description Esophagectomies are among the most invasive surgical procedures that highly influence health-related quality of life (HRQoL). Recent improvements have helped to achieve longer survival. Therefore, long-term postoperative HRQoL needs to be emphasized in addition to classic criterions like morbidity and mortality. We aimed to compare short and long-term HRQoL after open transthoracic esophagectomies (OTEs) and robotic-assisted minimally invasive esophagectomies (RAMIEs) in patients suffering from esophageal adenocarcinoma. Prospectively collected HRQoL-data (from the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire-C30 (EORTC QLQ-C30)) were correlated with clinical courses. Only patients suffering from minor postoperative complications (Clavien–Dindo Classification of < 2) after R0 Ivor-Lewis-procedures were included. Age, sex, body mass index (BMI), American Society of Anesthesiologists physical status-score (ASA-score), tumor stage, and perioperative therapy were used for propensity score matching (PSM). Twelve RAMIE and 29 OTE patients met the inclusion criteria. RAMIE patients reported significantly better emotional and social function while suffering from significantly less pain and less physical impairment four months after surgery. The long-term follow up confirmed the results. Long-term postoperative HRQoL and self-perception partly exceeded the levels of the healthy reference population. Minor operative trauma by robotic approaches resulted in significantly reduced physical impairments while improving HRQoL and self-perception, especially in the long-term. However, further long-term results are warranted to confirm this positive trend.
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spelling pubmed-76937022020-11-28 Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study Mehdorn, Anne-Sophie Möller, Thorben Franke, Frederike Richter, Florian Kersebaum, Jan-Niclas Becker, Thomas Egberts, Jan-Hendrik J Clin Med Article Esophagectomies are among the most invasive surgical procedures that highly influence health-related quality of life (HRQoL). Recent improvements have helped to achieve longer survival. Therefore, long-term postoperative HRQoL needs to be emphasized in addition to classic criterions like morbidity and mortality. We aimed to compare short and long-term HRQoL after open transthoracic esophagectomies (OTEs) and robotic-assisted minimally invasive esophagectomies (RAMIEs) in patients suffering from esophageal adenocarcinoma. Prospectively collected HRQoL-data (from the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire-C30 (EORTC QLQ-C30)) were correlated with clinical courses. Only patients suffering from minor postoperative complications (Clavien–Dindo Classification of < 2) after R0 Ivor-Lewis-procedures were included. Age, sex, body mass index (BMI), American Society of Anesthesiologists physical status-score (ASA-score), tumor stage, and perioperative therapy were used for propensity score matching (PSM). Twelve RAMIE and 29 OTE patients met the inclusion criteria. RAMIE patients reported significantly better emotional and social function while suffering from significantly less pain and less physical impairment four months after surgery. The long-term follow up confirmed the results. Long-term postoperative HRQoL and self-perception partly exceeded the levels of the healthy reference population. Minor operative trauma by robotic approaches resulted in significantly reduced physical impairments while improving HRQoL and self-perception, especially in the long-term. However, further long-term results are warranted to confirm this positive trend. MDPI 2020-10-30 /pmc/articles/PMC7693702/ /pubmed/33142987 http://dx.doi.org/10.3390/jcm9113513 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mehdorn, Anne-Sophie
Möller, Thorben
Franke, Frederike
Richter, Florian
Kersebaum, Jan-Niclas
Becker, Thomas
Egberts, Jan-Hendrik
Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study
title Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study
title_full Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study
title_fullStr Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study
title_full_unstemmed Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study
title_short Long-Term, Health-Related Quality of Life after Open and Robot-Assisted Ivor-Lewis Procedures—A Propensity Score-Matched Study
title_sort long-term, health-related quality of life after open and robot-assisted ivor-lewis procedures—a propensity score-matched study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693702/
https://www.ncbi.nlm.nih.gov/pubmed/33142987
http://dx.doi.org/10.3390/jcm9113513
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