High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results

The East Balkan swine (Sus scrofa) is the only aboriginal pig breed in Bulgaria, and it is indigenous to the eastern part of the country. The aim of the present study was to investigate East Balkan swine (EBS) in Bulgaria for serological evidence of hepatitis E virus (HEV). Sera from 171 swine from...

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Autores principales: Tsachev, Ilia, Baymakova, Magdalena, Pepovich, Roman, Palova, Nadezhda, Marutsov, Plamen, Gospodinova, Krasimira, Kundurzhiev, Todor, Ciccozzi, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693706/
https://www.ncbi.nlm.nih.gov/pubmed/33153218
http://dx.doi.org/10.3390/pathogens9110911
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author Tsachev, Ilia
Baymakova, Magdalena
Pepovich, Roman
Palova, Nadezhda
Marutsov, Plamen
Gospodinova, Krasimira
Kundurzhiev, Todor
Ciccozzi, Massimo
author_facet Tsachev, Ilia
Baymakova, Magdalena
Pepovich, Roman
Palova, Nadezhda
Marutsov, Plamen
Gospodinova, Krasimira
Kundurzhiev, Todor
Ciccozzi, Massimo
author_sort Tsachev, Ilia
collection PubMed
description The East Balkan swine (Sus scrofa) is the only aboriginal pig breed in Bulgaria, and it is indigenous to the eastern part of the country. The aim of the present study was to investigate East Balkan swine (EBS) in Bulgaria for serological evidence of hepatitis E virus (HEV). Sera from 171 swine from two parts of the country (northeastern and southeastern) were tested for anti-HEV IgG antibodies. The overall HEV seroprevalence was 82.5% (141/171), and for weaners it was 77.2% (44/57), for fattening pigs 79.0% (45/57), and for adults 91.2% (52/57). HEV positivity was higher in fattening pigs and adults compared to weaners: OR = 1.108 (95% CI: 0.456–2.692) and OR = 3.073 (95% CI: 1.016–9.294), respectively. This study provides the first evidence of exposure to HEV in EBS from Bulgaria.
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spelling pubmed-76937062020-11-28 High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results Tsachev, Ilia Baymakova, Magdalena Pepovich, Roman Palova, Nadezhda Marutsov, Plamen Gospodinova, Krasimira Kundurzhiev, Todor Ciccozzi, Massimo Pathogens Article The East Balkan swine (Sus scrofa) is the only aboriginal pig breed in Bulgaria, and it is indigenous to the eastern part of the country. The aim of the present study was to investigate East Balkan swine (EBS) in Bulgaria for serological evidence of hepatitis E virus (HEV). Sera from 171 swine from two parts of the country (northeastern and southeastern) were tested for anti-HEV IgG antibodies. The overall HEV seroprevalence was 82.5% (141/171), and for weaners it was 77.2% (44/57), for fattening pigs 79.0% (45/57), and for adults 91.2% (52/57). HEV positivity was higher in fattening pigs and adults compared to weaners: OR = 1.108 (95% CI: 0.456–2.692) and OR = 3.073 (95% CI: 1.016–9.294), respectively. This study provides the first evidence of exposure to HEV in EBS from Bulgaria. MDPI 2020-11-03 /pmc/articles/PMC7693706/ /pubmed/33153218 http://dx.doi.org/10.3390/pathogens9110911 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tsachev, Ilia
Baymakova, Magdalena
Pepovich, Roman
Palova, Nadezhda
Marutsov, Plamen
Gospodinova, Krasimira
Kundurzhiev, Todor
Ciccozzi, Massimo
High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results
title High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results
title_full High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results
title_fullStr High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results
title_full_unstemmed High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results
title_short High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results
title_sort high seroprevalence of hepatitis e virus infection among east balkan swine (sus scrofa) in bulgaria: preliminary results
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693706/
https://www.ncbi.nlm.nih.gov/pubmed/33153218
http://dx.doi.org/10.3390/pathogens9110911
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