Cargando…

Characterization and Therapeutic Potential of Bacteriophage-Encoded Polysaccharide Depolymerases with β Galactosidase Activity against Klebsiella pneumoniae K57 Capsular Type

Bacteriophages and phage enzymes are considered as possible alternatives to antibiotics in the treatment of infections caused by antibiotic-resistant bacteria. Due to the ability to cleave the capsular polysaccharides (CPS), one of the main virulence factors of Klebsiella pneumoniae, phage depolymer...

Descripción completa

Detalles Bibliográficos
Autores principales:	V. Volozhantsev, Nikolay, M. Shpirt, Anna, I. Borzilov, Alexander, V. Komisarova, Ekaterina, M. Krasilnikova, Valentina, S. Shashkov, Alexander, V. Verevkin, Vladimir, A. Knirel, Yuriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693772/ https://www.ncbi.nlm.nih.gov/pubmed/33113762 http://dx.doi.org/10.3390/antibiotics9110732

Ejemplares similares

Complete Genome Sequence of Klebsiella pneumoniae Bacteriophage KpS110, Encoding Five Tail-Associated Proteins with Putative Polysaccharide Depolymerase Domains
por: Volozhantsev, Nikolay V., et al.
Publicado: (2023)

Friunavirus Phage-Encoded Depolymerases Specific to Different Capsular Types of Acinetobacter baumannii
por: Timoshina, Olga Y., et al.
Publicado: (2023)

Complete Nucleotide Sequence of Klebsiella pneumoniae Bacteriophage vB_KpnM_KpV477
por: Komisarova, Ekaterina V., et al.
Publicado: (2017)

Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential
por: Gorodnichev, Roman B., et al.
Publicado: (2021)

Isolation of a Bacteriophage Specific for a New Capsular Type of Klebsiella pneumoniae and Characterization of Its Polysaccharide Depolymerase
por: Hsu, Chun-Ru, et al.
Publicado: (2013)

Characterisation of Bacteriophage-Encoded Depolymerases Selective for Key Klebsiella pneumoniae Capsular Exopolysaccharides
por: Blundell-Hunter, George, et al.
Publicado: (2021)

Capsule-Targeting Depolymerases Derived from Acinetobacter baumannii Prophage Regions
por: Drobiazko, Alena Y., et al.
Publicado: (2022)

Autographivirinae Bacteriophage Arno 160 Infects Pectobacterium carotovorum via Depolymerization of the Bacterial O-Polysaccharide
por: Shneider, Mikhail M., et al.
Publicado: (2020)

Protective Capacity of Monoclonal Antibodies against Acinetobacter baumannii K9 Capsular Polysaccharide
por: Karatovskaya, Anna, et al.
Publicado: (2023)

Specific Interaction of Novel Friunavirus Phages Encoding Tailspike Depolymerases with Corresponding Acinetobacter baumannii Capsular Types
por: Popova, A. V., et al.
Publicado: (2021)

Pectobacterium versatile Bacteriophage Possum: A Complex Polysaccharide-Deacetylating Tail Fiber as a Tool for Host Recognition in Pectobacterial Schitoviridae
por: Lukianova, Anna A., et al.
Publicado: (2022)

Morphologically Different Pectobacterium brasiliense Bacteriophages PP99 and PP101: Deacetylation of O-Polysaccharide by the Tail Spike Protein of Phage PP99 Accompanies the Infection
por: Lukianova, Anna A., et al.
Publicado: (2020)

Novel Acinetobacter baumannii Myovirus TaPaz Encoding Two Tailspike Depolymerases: Characterization and Host-Recognition Strategy
por: Shchurova, Anastasia S., et al.
Publicado: (2021)

Structural biology and functional features of phage-derived depolymerase Depo32 on Klebsiella pneumoniae with K2 serotype capsular polysaccharides
por: Cai, Ruopeng, et al.
Publicado: (2023)

Bacteriophages with depolymerase activity in the control of antibiotic resistant Klebsiella pneumoniae biofilms
por: Zurabov, Fedor, et al.
Publicado: (2023)

Periplasmic depolymerase provides insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides
por: Liston, Sean D., et al.
Publicado: (2018)

Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage
por: Dunstan, Rhys A., et al.
Publicado: (2021)

Immune Response to Conjugates of Fragments of the Type K9 Capsular Polysaccharide of Acinetobacter baumannii with Carrier Proteins
por: Rudenko, Natalia, et al.
Publicado: (2022)

Acinetobacter baumannii K106 and K112: Two Structurally and Genetically Related 6-Deoxy-l-talose-Containing Capsular Polysaccharides
por: Kasimova, Anastasiya A., et al.
Publicado: (2021)

Identification of three podoviruses infecting Klebsiella encoding capsule depolymerases that digest specific capsular types
por: Pan, Yi‐Jiun, et al.
Publicado: (2019)

Identification of three capsule depolymerases in a bacteriophage infecting Klebsiella pneumoniae capsular types K7, K20, and K27 and therapeutic application
por: Wu, Jia-Wen, et al.
Publicado: (2023)

Characterization of Novel Bacteriophage vB_KpnP_ZX1 and Its Depolymerases with Therapeutic Potential for K57 Klebsiella pneumoniae Infection
por: Li, Ping, et al.
Publicado: (2022)

Involvement of a Phage-Encoded Wzy Protein in the Polymerization of K127 Units To Form the Capsular Polysaccharide of Acinetobacter baumannii Isolate 36-1454
por: Arbatsky, Nikolay P., et al.
Publicado: (2022)

Structure of O-Polysaccharide and Lipid A of Pantoea Agglomerans 8488
por: Bulyhina, Tetiana V., et al.
Publicado: (2020)

The K46 and K5 capsular polysaccharides produced by Acinetobacter baumannii NIPH 329 and SDF have related structures and the side-chain non-ulosonic acids are 4-O-acetylated by phage-encoded O-acetyltransferases
por: Kenyon, Johanna J., et al.
Publicado: (2019)

Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases
por: Lin, Tzu-Lung, et al.
Publicado: (2022)

Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the gtr6 Glycosyltransferase Gene Leads To Susceptibility To Phage APK37.1
por: Timoshina, Olga Y., et al.
Publicado: (2023)

Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae
por: Maciejewska, Barbara, et al.
Publicado: (2023)

Identification of a Depolymerase Specific for K64-Serotype Klebsiella pneumoniae: Potential Applications in Capsular Typing and Treatment
por: Li, Jiayin, et al.
Publicado: (2021)

Therapeutic Application of Bacteriophage PHB02 and Its Putative Depolymerase Against Pasteurella multocida Capsular Type A in Mice
por: Chen, Yibao, et al.
Publicado: (2018)

Bacteriophage-Derived Depolymerases against Bacterial Biofilm
por: Topka-Bielecka, Gracja, et al.
Publicado: (2021)

Bacteriophage SRD2021 Recognizing Capsular Polysaccharide Shows Therapeutic Potential in Serotype K47 Klebsiella pneumoniae Infections
por: Hao, Guijuan, et al.
Publicado: (2021)

Synergistic Removal of Static and Dynamic Staphylococcus aureus Biofilms by Combined Treatment with a Bacteriophage Endolysin and a Polysaccharide Depolymerase
por: Olsen, Nanna M. C., et al.
Publicado: (2018)

Genetic analysis of capsular polysaccharide synthesis gene clusters in 79 capsular types of Klebsiella spp
por: Pan, Yi-Jiun, et al.
Publicado: (2015)

Novel Acinetobacter baumannii Bacteriophage Aristophanes Encoding Structural Polysaccharide Deacetylase
por: Timoshina, Olga Yu., et al.
Publicado: (2021)

Elucidation of a masked repeating structure of the O-specific polysaccharide of the halotolerant soil bacteria Azospirillum halopraeferens Au4
por: Sigida, Elena N, et al.
Publicado: (2016)

Identification of a capsular variant and characterization of capsular acetylation in Klebsiella pneumoniae PLA-associated type K57
por: Hsu, Chun-Ru, et al.
Publicado: (2016)

Genetic and structural identification of an O-acyltransferase gene (oacC) responsible for the 3/4-O-acetylation on rhamnose III in Shigella flexneri serotype 6
por: Knirel, Yuriy A, et al.
Publicado: (2014)

Inhibition of Klebsiella pneumoniae Growth and Capsular Polysaccharide Biosynthesis by Fructus mume
por: Lin, Tien-Huang, et al.
Publicado: (2013)

Anti-Biofilm Activity: A Function of Klebsiella pneumoniae Capsular Polysaccharide
por: Dos Santos Goncalves, Marina, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vk89lacc8kqa2it059uijf5hjk