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Vacuum Compression Molding as a Screening Tool to Investigate Carrier Suitability for Hot-Melt Extrusion Formulations

Hot-melt extrusion (HME) is the most preferred and effective method for manufacturing amorphous solid dispersions at production scale, but it consumes large amounts of samples when used for formulation development. Herein, we show a novel approach to screen the polymers by overcoming the disadvantag...

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Detalles Bibliográficos
Autores principales:	Shadambikar, Gauri, Kipping, Thomas, Di-Gallo, Nicole, Elia, Alessandro-Giuseppe, Knüttel, Anja-Nadine, Treffer, Daniel, Repka, Michael. A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693833/ https://www.ncbi.nlm.nih.gov/pubmed/33114382 http://dx.doi.org/10.3390/pharmaceutics12111019

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