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Indoxyl Sulfate, a Tubular Toxin, Contributes to the Development of Chronic Kidney Disease

Indoxyl sulfate (IS), a uremic toxin, causes chronic kidney disease (CKD) progression via its tubulotoxicity. After cellular uptake, IS directly induces apoptotic and necrotic cell death of tubular cells. Additionally, IS increases oxidative stress and decreases antioxidant capacity, which are assoc...

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Detalles Bibliográficos
Autores principales:	Cheng, Tong-Hong, Ma, Ming-Chieh, Liao, Min-Tser, Zheng, Cai-Mei, Lu, Kuo-Cheng, Liao, Chun-Hou, Hou, Yi-Chou, Liu, Wen-Chih, Lu, Chien-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693919/ https://www.ncbi.nlm.nih.gov/pubmed/33138205 http://dx.doi.org/10.3390/toxins12110684

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