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Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications
Multifunctional micro- and nanoparticles have potential uses in advanced detection methods, such as the combined separation and detection of biomolecules. Combining multiple tasks is possible but requires the specific tailoring of these particles during synthesis or further functionalization. Here,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693944/ https://www.ncbi.nlm.nih.gov/pubmed/33121012 http://dx.doi.org/10.3390/nano10112136 |
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author | Bedford, Erin E. Méthivier, Christophe Pradier, Claire-Marie Gu, Frank Boujday, Souhir |
author_facet | Bedford, Erin E. Méthivier, Christophe Pradier, Claire-Marie Gu, Frank Boujday, Souhir |
author_sort | Bedford, Erin E. |
collection | PubMed |
description | Multifunctional micro- and nanoparticles have potential uses in advanced detection methods, such as the combined separation and detection of biomolecules. Combining multiple tasks is possible but requires the specific tailoring of these particles during synthesis or further functionalization. Here, we synthesized nanostructured gold shells on magnetic particle cores and demonstrated the use of them in surface-enhanced Raman scattering (SERS). To grow the gold shells, gold seeds were bound to silica-coated iron oxide aggregate particles. We explored different functional groups on the surface to achieve different interactions with gold seeds. Then, we used an aqueous cetyltrimethylammonium bromide (CTAB)-based strategy to grow the seeds into spikes. We investigated the influence of the surface chemistry on seed attachment and on further growth of spikes. We also explored different experimental conditions to achieve either spiky or bumpy plasmonic structures on the particles. We demonstrated that the particles showed SERS enhancement of a model Raman probe molecule, 2-mercaptopyrimidine, on the order of 10(4). We also investigated the impact of gold shell morphology—spiky or bumpy—on SERS enhancements and on particle stability over time. We found that spiky shells lead to greater enhancements, however their high aspect ratio structures are less stable and morphological changes occur more quickly than observed with bumpy shells. |
format | Online Article Text |
id | pubmed-7693944 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76939442020-11-28 Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications Bedford, Erin E. Méthivier, Christophe Pradier, Claire-Marie Gu, Frank Boujday, Souhir Nanomaterials (Basel) Article Multifunctional micro- and nanoparticles have potential uses in advanced detection methods, such as the combined separation and detection of biomolecules. Combining multiple tasks is possible but requires the specific tailoring of these particles during synthesis or further functionalization. Here, we synthesized nanostructured gold shells on magnetic particle cores and demonstrated the use of them in surface-enhanced Raman scattering (SERS). To grow the gold shells, gold seeds were bound to silica-coated iron oxide aggregate particles. We explored different functional groups on the surface to achieve different interactions with gold seeds. Then, we used an aqueous cetyltrimethylammonium bromide (CTAB)-based strategy to grow the seeds into spikes. We investigated the influence of the surface chemistry on seed attachment and on further growth of spikes. We also explored different experimental conditions to achieve either spiky or bumpy plasmonic structures on the particles. We demonstrated that the particles showed SERS enhancement of a model Raman probe molecule, 2-mercaptopyrimidine, on the order of 10(4). We also investigated the impact of gold shell morphology—spiky or bumpy—on SERS enhancements and on particle stability over time. We found that spiky shells lead to greater enhancements, however their high aspect ratio structures are less stable and morphological changes occur more quickly than observed with bumpy shells. MDPI 2020-10-27 /pmc/articles/PMC7693944/ /pubmed/33121012 http://dx.doi.org/10.3390/nano10112136 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bedford, Erin E. Méthivier, Christophe Pradier, Claire-Marie Gu, Frank Boujday, Souhir Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications |
title | Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications |
title_full | Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications |
title_fullStr | Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications |
title_full_unstemmed | Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications |
title_short | Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications |
title_sort | nanostructured and spiky gold shell growth on magnetic particles for sers applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693944/ https://www.ncbi.nlm.nih.gov/pubmed/33121012 http://dx.doi.org/10.3390/nano10112136 |
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