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Detection of Pathogenic Isoforms of IKZF1 in Leukemic Cell Lines and Acute Lymphoblastic Leukemia Samples: Identification of a Novel Truncated IKZF1 Transcript in SUP-B15

SIMPLE SUMMARY: Abnormal RNA splicing plays a fundamental role in leukemogenesis in acute lymphoblastic leukemia (ALL). Many cases of high-risk B-cell ALL cases, including BCR-ABL1+ and BCR-ABL1-like ALL, share a common molecular mechanism of aberrant fusion transcripts involving tyrosine kinase gen...

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Detalles Bibliográficos
Autores principales:	Zhao, Weiqiang, Li, Ying, Yao, Chenjiao, Zhang, Guojuan, Zhao, Kevin Y., Chen, Wei, Ru, Peng, Pan, Xiaokang, Tu, Huolin, Jones, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693987/ https://www.ncbi.nlm.nih.gov/pubmed/33126432 http://dx.doi.org/10.3390/cancers12113161

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