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Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology

Cellulose is one of the most hydrophilic polymers with sufficient water holding capacity but it is unstable in aqueous conditions and it swells. Cellulose itself is not suitable for electrospun nanofibers’ formation due to high swelling, viscosity, and lower conductivity. Carboxymethyl cellulose (CM...

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Autores principales: Hashmi, Motahira, Ullah, Sana, Ullah, Azeem, Akmal, Muhammad, Saito, Yusuke, Hussain, Nadir, Ren, Xuehong, Kim, Ick Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694076/
https://www.ncbi.nlm.nih.gov/pubmed/33137972
http://dx.doi.org/10.3390/polym12112524
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author Hashmi, Motahira
Ullah, Sana
Ullah, Azeem
Akmal, Muhammad
Saito, Yusuke
Hussain, Nadir
Ren, Xuehong
Kim, Ick Soo
author_facet Hashmi, Motahira
Ullah, Sana
Ullah, Azeem
Akmal, Muhammad
Saito, Yusuke
Hussain, Nadir
Ren, Xuehong
Kim, Ick Soo
author_sort Hashmi, Motahira
collection PubMed
description Cellulose is one of the most hydrophilic polymers with sufficient water holding capacity but it is unstable in aqueous conditions and it swells. Cellulose itself is not suitable for electrospun nanofibers’ formation due to high swelling, viscosity, and lower conductivity. Carboxymethyl cellulose (CMC) is also super hydrophilic polymer, however it has the same trend for nanofibers formation as that of cellulose. Due to the above-stated reasons, applications of CMC are quite limited in nanotechnology. In recent research, loading of CMC was optimized for electrospun tri-component polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), and carboxymethyl cellulose (CMC) nanofibers aim at widening its area of applications. PVA is a water-soluble polymer with a wide range of applications in water filtration, biomedical, and environmental engineering, and with the advantage of easy process ability. However, it was observed that only PVA was not sufficient to produce PVA/CMC nanofibers via electrospinning. To increase spinnability of PVA/CMC nanofibers, PVP was selected as the best available option because of its higher conductivity and water solubility. Weight ratios of CMC and PVP were optimized to produce uniform nanofibers with continuous production as well. It was observed that at a weight ratio of PVP 12 and CMC 3 was at the highest possible loading to produce smooth nanofibers.
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spelling pubmed-76940762020-11-28 Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology Hashmi, Motahira Ullah, Sana Ullah, Azeem Akmal, Muhammad Saito, Yusuke Hussain, Nadir Ren, Xuehong Kim, Ick Soo Polymers (Basel) Article Cellulose is one of the most hydrophilic polymers with sufficient water holding capacity but it is unstable in aqueous conditions and it swells. Cellulose itself is not suitable for electrospun nanofibers’ formation due to high swelling, viscosity, and lower conductivity. Carboxymethyl cellulose (CMC) is also super hydrophilic polymer, however it has the same trend for nanofibers formation as that of cellulose. Due to the above-stated reasons, applications of CMC are quite limited in nanotechnology. In recent research, loading of CMC was optimized for electrospun tri-component polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), and carboxymethyl cellulose (CMC) nanofibers aim at widening its area of applications. PVA is a water-soluble polymer with a wide range of applications in water filtration, biomedical, and environmental engineering, and with the advantage of easy process ability. However, it was observed that only PVA was not sufficient to produce PVA/CMC nanofibers via electrospinning. To increase spinnability of PVA/CMC nanofibers, PVP was selected as the best available option because of its higher conductivity and water solubility. Weight ratios of CMC and PVP were optimized to produce uniform nanofibers with continuous production as well. It was observed that at a weight ratio of PVP 12 and CMC 3 was at the highest possible loading to produce smooth nanofibers. MDPI 2020-10-29 /pmc/articles/PMC7694076/ /pubmed/33137972 http://dx.doi.org/10.3390/polym12112524 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hashmi, Motahira
Ullah, Sana
Ullah, Azeem
Akmal, Muhammad
Saito, Yusuke
Hussain, Nadir
Ren, Xuehong
Kim, Ick Soo
Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology
title Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology
title_full Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology
title_fullStr Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology
title_full_unstemmed Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology
title_short Optimized Loading of Carboxymethyl Cellulose (CMC) in Tri-component Electrospun Nanofibers Having Uniform Morphology
title_sort optimized loading of carboxymethyl cellulose (cmc) in tri-component electrospun nanofibers having uniform morphology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694076/
https://www.ncbi.nlm.nih.gov/pubmed/33137972
http://dx.doi.org/10.3390/polym12112524
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