Cargando…

The Modulatory Role of Vitamin C in Boldenone Undecylenate Induced Testicular Oxidative Damage and Androgen Receptor Dysregulation in Adult Male Rats

Background: This study explored the effect of vitamin C (Vit-C) administration on the reproductive function of adult male Wistar rats injected with boldenone undecylenate (BOL). Methods: Rats were randomly assigned into control, vehicle control, Vit-C (120 mg/kg b.wt./day, orally), BOL (received 5 m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Behairy, Amany, El-Sharkawy, Nabela I., Saber, Taghred M., Soliman, Mohamed Mohamed, Metwally, Mohamed M.M., Abd El-Rahman, Ghada I., Abd-Elhakim, Yasmina M., El Deib, Maha M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694087/ https://www.ncbi.nlm.nih.gov/pubmed/33126548 http://dx.doi.org/10.3390/antiox9111053

Ejemplares similares

Boldenone Undecylenate-Mediated Hepatorenal Impairment by Oxidative Damage and Dysregulation of Heat Shock Protein 90 and Androgen Receptors Expressions: Vitamin C Preventive Role
por: Behairy, Amany, et al.
Publicado: (2021)

Forensic toxicological study on adipocere formation in submerged cadavers of female albino rats intoxicated with cadmium
por: El-Sharkawy, Nabela I., et al.
Publicado: (2019)

Time-dependent expression of high-mobility group box-1 and toll-like receptors proteins as potential determinants of skin wound age in rats: Forensic implication
por: Abd-Elhakim, Yasmina M., et al.
Publicado: (2022)

Quercetin Abates Aluminum Trioxide Nanoparticles and Lead Acetate Induced Altered Sperm Quality, Testicular Oxidative Damage, and Sexual Hormones Disruption in Male Rats
por: Behairy, Amany, et al.
Publicado: (2022)

Neurobehavioral Responses and Toxic Brain Reactions of Juvenile Rats Exposed to Iprodione and Chlorpyrifos, Alone and in a Mixture
por: Abd-Elhakim, Yasmina M., et al.
Publicado: (2023)

Saussurea lappa Ethanolic Extract Attenuates Triamcinolone Acetonide-Induced Pulmonary and Splenic Tissue Damage in Rats via Modulation of Oxidative Stress, Inflammation, and Apoptosis
por: Abd El-Rahman, Ghada I., et al.
Publicado: (2020)

Toll-like receptors and nuclear factor kappa B signaling pathway involvement in hepatorenal oxidative damage induced by some food preservatives in rats
por: Abd-Elhakim, Yasmina M., et al.
Publicado: (2023)

The palliative effect of mulberry leaf and olive leaf ethanolic extracts on hepatic CYP2E1 and caspase-3 immunoexpression and oxidative damage induced by paracetamol in male rats
por: Fadil, Hosny Abd El, et al.
Publicado: (2023)

Dietary Parsley Seed Mitigates Methomyl-Induced Impaired Growth Performance, Hemato-Immune Suppression, Oxidative Stress, Hepato-Renal Damage, and Pseudomonas aeruginosa Susceptibility in Oreochromis niloticus
por: El-Houseiny, Walaa, et al.
Publicado: (2022)

Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats
por: Abd-Elhakim, Yasmina M., et al.
Publicado: (2021)

Grape Seed Proanthocyanidin Ameliorates Cardiac Toxicity Induced by Boldenone Undecylenate through Inhibition of NADPH Oxidase and Reduction in the Expression of NOX2 and NOX4
por: Tousson, Ehab, et al.
Publicado: (2018)

Single step biotransformation of corn oil phytosterols to boldenone by a newly isolated Pseudomonas aeruginosa
por: Eisa, Mohamed, et al.
Publicado: (2016)

Green Synthesized Zinc Oxide Nanoparticles Using Moringa olifera Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats
por: Mostafa-Hedeab, Gomaa, et al.
Publicado: (2023)

Palliative Effect of Resveratrol against Nanosized Iron Oxide-Induced Oxidative Stress and Steroidogenesis-Related Genes Dysregulation in Testicular Tissue of Adult Male Rats
por: Ahmed, Mona M., et al.
Publicado: (2022)

Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats
por: Abd El-Hakim, Yasmina M., et al.
Publicado: (2020)

Ameliorative effects of quercetin against hepatic toxicity of oral sub-chronic co-exposure to aluminum oxide nanoparticles and lead-acetate in male rats
por: Abo-EL-Sooud, Khaled, et al.
Publicado: (2022)

Correction to: Ameliorative effects of quercetin against hepatic toxicity of oral sub‑chronic co‑exposure to aluminum oxide nanoparticles and lead‑acetate in male rats
por: Abo-EL-Sooud, Khaled, et al.
Publicado: (2022)

Bee venom (Apis mellifera L.) rescues zinc oxide nanoparticles induced neurobehavioral and neurotoxic impact via controlling neurofilament and GAP-43 in rat brain
por: Eleiwa, Naglaa Z. H., et al.
Publicado: (2023)

The Behavioral and Neurochemical Changes Induced by Boldenone and/or Tramadol in Adult Male Rats
por: Mowaad, Noha A., et al.
Publicado: (2022)

Sustained Functioning Impairments and Oxidative Stress with Neurobehavioral Dysfunction Associated with Oral Nicotine Exposure in the Brain of a Murine Model of Ehrlich Ascites Carcinoma: Modifying the Antioxidant Role of Chlorella vulgaris
por: Mohamed, Amany Abdel-Rahman, et al.
Publicado: (2022)

Evaluation of boldenone as a growth promoter in broilers: safety and meat quality aspects
por: Elmajdoub, Abdelrazzag, et al.
Publicado: (2016)

Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review
por: El-Saber Batiha, Gaber, et al.
Publicado: (2020)

Embryotoxic and Teratogenic Effects of Tartrazine in Rats
por: Hashem, Mohamed Mohammed, et al.
Publicado: (2019)

Restorative effects of gallic acid against sub-chronic hepatic toxicity of co-exposure to zinc oxide nanoparticles and arsenic trioxide in male rats
por: Abo-EL-Sooud, Khaled, et al.
Publicado: (2023)

Fungicidal PMMA-Undecylenic Acid Composites
por: Petrović, Milica, et al.
Publicado: (2018)

A Rare Case of Orthograde Retrieval of Extruded Instrument following Periapical Tissue Healing
por: Elhakim, Ahmed, et al.
Publicado: (2022)

Estimation of ultrasound reference values for the ulnar nerve fascicular number and cross-sectional area in young males: A cross-sectional study
por: Bedewi, Mohamed Abdelmohsen, et al.
Publicado: (2017)

Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of Euphorbia peplus Methanolic Extract in Rats
por: Abd-Elhakim, Yasmina M., et al.
Publicado: (2019)

Evaluation of the impact of percutaneous coronary intervention of chronic total occlusion on regional myocardial function using strain echocardiography
por: Kholeif, Abd ElFattah, et al.
Publicado: (2019)

Effects of Co-Exposure of Nanoparticles and Metals on Different Organisms: A Review
por: Abd-Elhakim, Yasmina M., et al.
Publicado: (2021)

Therapeutic Effect of Murine Bone Marrow-Derived Mesenchymal Stromal/Stem Cells and Human Placental Extract on Testicular Toxicity Resulting from Doxorubicin in Rats
por: AbdRabou, Mervat Ahmed, et al.
Publicado: (2021)

Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis
por: Day, Zoe I., et al.
Publicado: (2022)

Ocular Inserts of Voriconazole-Loaded Proniosomal Gels: Formulation, Evaluation and Microbiological Studies
por: El-Emam, Ghada Ahmed, et al.
Publicado: (2020)

Laser acupuncture improving functional chronic constipation in children: a randomized controlled trial
por: Abd El Azeem, Amany M., et al.
Publicado: (2023)

Predictors of azathioprine toxicity in children with autoimmune hepatitis
por: Behairy, Behairy El-Sayed, et al.
Publicado: (2021)

Influence of Feeding Quinoa (Chenopodium quinoa) Seeds and Prickly Pear Fruit (Opuntia ficus indica) Peel on the Immune Response and Resistance to Aeromonas sobria Infection in Nile Tilapia (Oreochromis niloticus)
por: Ahmed, Shaimaa A. A., et al.
Publicado: (2020)

Hexosomes with Undecylenic Acid Efficient against Candida albicans
por: Mionić Ebersold, Marijana, et al.
Publicado: (2018)

Hormonal and inflammatory modulatory effects of hesperidin in hyperthyroidism-modeled rats
por: Ashry, Mahmoud, et al.
Publicado: (2023)

Clinical Benefits of Biochemical Markers of Fibrosis in Egyptian Children With Chronic Liver Diseases
por: Abdel-Ghaffar, Tawhida Y., et al.
Publicado: (2010)

Augmentation cystoplasty in dogs: A comparative study of different tunica vaginalis grafts
por: Ahmed, Mahmoud F., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ed4jkg43940rigrcguqb3cpjoa