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Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694143/ https://www.ncbi.nlm.nih.gov/pubmed/33137889 http://dx.doi.org/10.3390/antibiotics9110748 |
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author | Džupová, Olga Kulichová, Jana Beneš, Jiří |
author_facet | Džupová, Olga Kulichová, Jana Beneš, Jiří |
author_sort | Džupová, Olga |
collection | PubMed |
description | Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can mimic metastases and further increase suspicion for malignancy. A case of severe disseminated pelvic actinomycosis associated with intrauterine device is described here. The patient presented with a pelvic mass mimicking a tumour, bilateral ureteral obstruction, ascites, multinodular involvement of the liver, lungs and spleen, inferior vena cava thrombosis and extreme cachexia. Actinomycosis was diagnosed by liver biopsy and confirmed by culture of Actinomyces naeslundii from extracted intrauterine contraceptive device (IUD). Prolonged treatment with aminopenicillin and surgery resulted in recovery with moderate sequelae. |
format | Online Article Text |
id | pubmed-7694143 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76941432020-11-28 Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii Džupová, Olga Kulichová, Jana Beneš, Jiří Antibiotics (Basel) Brief Report Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can mimic metastases and further increase suspicion for malignancy. A case of severe disseminated pelvic actinomycosis associated with intrauterine device is described here. The patient presented with a pelvic mass mimicking a tumour, bilateral ureteral obstruction, ascites, multinodular involvement of the liver, lungs and spleen, inferior vena cava thrombosis and extreme cachexia. Actinomycosis was diagnosed by liver biopsy and confirmed by culture of Actinomyces naeslundii from extracted intrauterine contraceptive device (IUD). Prolonged treatment with aminopenicillin and surgery resulted in recovery with moderate sequelae. MDPI 2020-10-29 /pmc/articles/PMC7694143/ /pubmed/33137889 http://dx.doi.org/10.3390/antibiotics9110748 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Brief Report Džupová, Olga Kulichová, Jana Beneš, Jiří Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii |
title | Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii |
title_full | Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii |
title_fullStr | Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii |
title_full_unstemmed | Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii |
title_short | Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii |
title_sort | disseminated pelvic actinomycosis caused by actinomyces naeslundii |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694143/ https://www.ncbi.nlm.nih.gov/pubmed/33137889 http://dx.doi.org/10.3390/antibiotics9110748 |
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