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Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii

Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can...

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Detalles Bibliográficos
Autores principales: Džupová, Olga, Kulichová, Jana, Beneš, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694143/
https://www.ncbi.nlm.nih.gov/pubmed/33137889
http://dx.doi.org/10.3390/antibiotics9110748
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author Džupová, Olga
Kulichová, Jana
Beneš, Jiří
author_facet Džupová, Olga
Kulichová, Jana
Beneš, Jiří
author_sort Džupová, Olga
collection PubMed
description Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can mimic metastases and further increase suspicion for malignancy. A case of severe disseminated pelvic actinomycosis associated with intrauterine device is described here. The patient presented with a pelvic mass mimicking a tumour, bilateral ureteral obstruction, ascites, multinodular involvement of the liver, lungs and spleen, inferior vena cava thrombosis and extreme cachexia. Actinomycosis was diagnosed by liver biopsy and confirmed by culture of Actinomyces naeslundii from extracted intrauterine contraceptive device (IUD). Prolonged treatment with aminopenicillin and surgery resulted in recovery with moderate sequelae.
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spelling pubmed-76941432020-11-28 Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii Džupová, Olga Kulichová, Jana Beneš, Jiří Antibiotics (Basel) Brief Report Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can mimic metastases and further increase suspicion for malignancy. A case of severe disseminated pelvic actinomycosis associated with intrauterine device is described here. The patient presented with a pelvic mass mimicking a tumour, bilateral ureteral obstruction, ascites, multinodular involvement of the liver, lungs and spleen, inferior vena cava thrombosis and extreme cachexia. Actinomycosis was diagnosed by liver biopsy and confirmed by culture of Actinomyces naeslundii from extracted intrauterine contraceptive device (IUD). Prolonged treatment with aminopenicillin and surgery resulted in recovery with moderate sequelae. MDPI 2020-10-29 /pmc/articles/PMC7694143/ /pubmed/33137889 http://dx.doi.org/10.3390/antibiotics9110748 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Džupová, Olga
Kulichová, Jana
Beneš, Jiří
Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
title Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
title_full Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
title_fullStr Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
title_full_unstemmed Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
title_short Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii
title_sort disseminated pelvic actinomycosis caused by actinomyces naeslundii
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694143/
https://www.ncbi.nlm.nih.gov/pubmed/33137889
http://dx.doi.org/10.3390/antibiotics9110748
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