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Poziotinib Inhibits the Efflux Activity of the ABCB1 and ABCG2 Transporters and the Expression of the ABCG2 Transporter Protein in Multidrug Resistant Colon Cancer Cells

SIMPLE SUMMARY: Globally, colorectal cancer (CRC) is a leading cause of cancer deaths and chemotherapy, in combination with radiotherapy when appropriate, is used to treat the majority of CRC patients. However, the acquisition or development of drug resistance can decrease, or even abolish, the effi...

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Detalles Bibliográficos
Autores principales:	Zhang, Yongchao, Wu, Zhuo-Xun, Yang, Yuqi, Wang, Jing-Quan, Li, Jun, Sun, Zoey, Teng, Qiu-Xu, Ashby, Charles R., Yang, Dong-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694178/ https://www.ncbi.nlm.nih.gov/pubmed/33158067 http://dx.doi.org/10.3390/cancers12113249

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