Amyotrophic Lateral Sclerosis and Autophagy: Dysfunction and Therapeutic Targeting

Over the past 20 years, there has been a drastically increased understanding of the genetic basis of Amyotrophic Lateral Sclerosis. Despite the identification of more than 40 different ALS-causing mutations, the accumulation of neurotoxic misfolded proteins, inclusions, and aggregates within motor n...

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Detalles Bibliográficos
Autores principales: Amin, Azin, Perera, Nirma D., Beart, Philip M., Turner, Bradley J., Shabanpoor, Fazel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694295/
https://www.ncbi.nlm.nih.gov/pubmed/33158177
http://dx.doi.org/10.3390/cells9112413

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