Reversibility of hAT-MSCs phenotypic and metabolic changes after exposure to and withdrawal from HCC-conditioned medium through regulation of the ROS/MAPK/HIF-1α signaling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) play an important role in tumor progression; concomitantly, MSCs also undergo profound changes in the tumor microenvironment (TME). These changes can directly impact the application and efficacy of MSC-based anti-tumor therapy. However, few studies have focu...

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Detalles Bibliográficos
Autores principales: Wang, Chenyang, Hu, Jie, Chen, Zheng, Wang, Yifan, Lu, Sinan, Zhang, Yuan, Li, Yufeng, Xiang, Yucheng, Ji, Yutian, Zeng, Cheng, Ding, Yuan, Wang, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694319/
https://www.ncbi.nlm.nih.gov/pubmed/33246501
http://dx.doi.org/10.1186/s13287-020-02010-0

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