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Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters

A set of 6- to 24-valent clusters was constructed with terminal deoxynojirimycin (DNJ) inhibitory heads through C6 or C9 linkers by way of Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions between mono- or trivalent azido-armed iminosugars and calix[8]arene scaffolds differing in their va...

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Detalles Bibliográficos
Autores principales:	Schneider, Jérémy P., Tommasone, Stefano, Della Sala, Paolo, Gaeta, Carmine, Talotta, Carmen, Tarnus, Céline, Neri, Placido, Bodlenner, Anne, Compain, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694328/ https://www.ncbi.nlm.nih.gov/pubmed/33167387 http://dx.doi.org/10.3390/ph13110366

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