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BAG3 Proteomic Signature under Proteostasis Stress
The multifunctional HSP70 co-chaperone BAG3 (BCL-2-associated athanogene 3) represents a key player in the quality control of the cellular proteostasis network. In response to stress, BAG3 specifically targets aggregation-prone proteins to the perinuclear aggresome and promotes their degradation via...
Autores principales: | Hiebel, Christof, Stürner, Elisabeth, Hoffmeister, Meike, Tascher, Georg, Schwarz, Mario, Nagel, Heike, Behrends, Christian, Münch, Christian, Behl, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694386/ https://www.ncbi.nlm.nih.gov/pubmed/33158300 http://dx.doi.org/10.3390/cells9112416 |
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