Cargando…
An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness
Background: Difficulty modulating sensory input related to multi-sensory integration dysfunction, specifically the sensory over-responsive (SOR) type, is associated with psychological distress and hyperalgesia in children and adults. Scares reports suggest atypical autonomic nervous system (ANS) rea...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694392/ https://www.ncbi.nlm.nih.gov/pubmed/33167362 http://dx.doi.org/10.3390/brainsci10110819 |
_version_ | 1783614967064297472 |
---|---|
author | Bar-Shalita, Tami Ben-Ziv, Nurit Granovsky, Yelena Weissman-Fogel, Irit |
author_facet | Bar-Shalita, Tami Ben-Ziv, Nurit Granovsky, Yelena Weissman-Fogel, Irit |
author_sort | Bar-Shalita, Tami |
collection | PubMed |
description | Background: Difficulty modulating sensory input related to multi-sensory integration dysfunction, specifically the sensory over-responsive (SOR) type, is associated with psychological distress and hyperalgesia in children and adults. Scares reports suggest atypical autonomic nervous system (ANS) reactivity to innocuous sensory stimuli in children with SOR. Thus, the ANS may contribute to sensory stimuli responses and psychological distress. This exploratory study aimed to characterize the ANS reactivity to single and dual pain stimulation, and in relation to psychological distress in adults with SOR. Methods: Healthy women with SOR (n = 9) vs. without SOR (n = 9) underwent two runs of single pain stimulation and a third run comprised of dual pain stimulation. Pain was self-rated, while heart rate variability was measured and analyzed in the time and frequency domains. In addition, questionnaires assessing anxiety and somatization were utilized. Results: While controls demonstrated a vagal tone withdrawal (root mean square of successive differences in R-R-intervals; (RMSSD)) p = 0.029 from base-line to the third run, this was absent in the SOR group. However, no group differences were found in pain ratings. Furthermore, groups differed in the correlations between R-R mean and the level of both anxiety (p = 0.006) and somatization (p < 0.001); while in the SOR group, higher levels of anxiety and somatization correlated with shorter R-R intervals, the opposite was found in the control group. Conclusions: This is the first study to demonstrate in women with SOR atypical vagal tone reactivity to challenging pain load. Vagal tone reactivity is related to both pain ratings and psychological distress. |
format | Online Article Text |
id | pubmed-7694392 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76943922020-11-28 An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness Bar-Shalita, Tami Ben-Ziv, Nurit Granovsky, Yelena Weissman-Fogel, Irit Brain Sci Brief Report Background: Difficulty modulating sensory input related to multi-sensory integration dysfunction, specifically the sensory over-responsive (SOR) type, is associated with psychological distress and hyperalgesia in children and adults. Scares reports suggest atypical autonomic nervous system (ANS) reactivity to innocuous sensory stimuli in children with SOR. Thus, the ANS may contribute to sensory stimuli responses and psychological distress. This exploratory study aimed to characterize the ANS reactivity to single and dual pain stimulation, and in relation to psychological distress in adults with SOR. Methods: Healthy women with SOR (n = 9) vs. without SOR (n = 9) underwent two runs of single pain stimulation and a third run comprised of dual pain stimulation. Pain was self-rated, while heart rate variability was measured and analyzed in the time and frequency domains. In addition, questionnaires assessing anxiety and somatization were utilized. Results: While controls demonstrated a vagal tone withdrawal (root mean square of successive differences in R-R-intervals; (RMSSD)) p = 0.029 from base-line to the third run, this was absent in the SOR group. However, no group differences were found in pain ratings. Furthermore, groups differed in the correlations between R-R mean and the level of both anxiety (p = 0.006) and somatization (p < 0.001); while in the SOR group, higher levels of anxiety and somatization correlated with shorter R-R intervals, the opposite was found in the control group. Conclusions: This is the first study to demonstrate in women with SOR atypical vagal tone reactivity to challenging pain load. Vagal tone reactivity is related to both pain ratings and psychological distress. MDPI 2020-11-05 /pmc/articles/PMC7694392/ /pubmed/33167362 http://dx.doi.org/10.3390/brainsci10110819 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Brief Report Bar-Shalita, Tami Ben-Ziv, Nurit Granovsky, Yelena Weissman-Fogel, Irit An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness |
title | An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness |
title_full | An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness |
title_fullStr | An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness |
title_full_unstemmed | An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness |
title_short | An Exploratory Study Testing Autonomic Reactivity to Pain in Women with Sensory Over-Responsiveness |
title_sort | exploratory study testing autonomic reactivity to pain in women with sensory over-responsiveness |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694392/ https://www.ncbi.nlm.nih.gov/pubmed/33167362 http://dx.doi.org/10.3390/brainsci10110819 |
work_keys_str_mv | AT barshalitatami anexploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT benzivnurit anexploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT granovskyyelena anexploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT weissmanfogelirit anexploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT barshalitatami exploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT benzivnurit exploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT granovskyyelena exploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness AT weissmanfogelirit exploratorystudytestingautonomicreactivitytopaininwomenwithsensoryoverresponsiveness |