Investigation of de novo mutations in a schizophrenia case-parent trio by induced pluripotent stem cell-based in vitro disease modeling: convergence of schizophrenia- and autism-related cellular phenotypes

BACKGROUND: De novo mutations (DNMs) have been implicated in the etiology of schizophrenia (SZ), a chronic debilitating psychiatric disorder characterized by hallucinations, delusions, cognitive dysfunction, and decreased community functioning. Several DNMs have been identified by examining SZ cases...

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Detalles Bibliográficos
Autores principales: Hathy, Edit, Szabó, Eszter, Varga, Nóra, Erdei, Zsuzsa, Tordai, Csongor, Czehlár, Boróka, Baradits, Máté, Jezsó, Bálint, Koller, Júlia, Nagy, László, Molnár, Mária Judit, Homolya, László, Nemoda, Zsófia, Apáti, Ágota, Réthelyi, János M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694414/
https://www.ncbi.nlm.nih.gov/pubmed/33246498
http://dx.doi.org/10.1186/s13287-020-01980-5

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