Co-Application of Eugenol and QX-314 Elicits the Prolonged Blockade of Voltage-Gated Sodium Channels in Nociceptive Trigeminal Ganglion Neurons

Local anesthetics (LAs) can completely block nociception by inhibiting voltage-gated sodium channels (VGSCs), and thus, blocking action potentials (APs) within sensory neurons. As one of the several LAs, eugenol is used for dental pain treatment. It reportedly features multiple functions in regulati...

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Detalles Bibliográficos
Autores principales: Hwang, Sung-Min, Lee, Kihwan, Im, Sang-Taek, Go, Eun Jin, Kim, Yong Ho, Park, Chul-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694476/
https://www.ncbi.nlm.nih.gov/pubmed/33167484
http://dx.doi.org/10.3390/biom10111513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694476/
https://www.ncbi.nlm.nih.gov/pubmed/33167484
http://dx.doi.org/10.3390/biom10111513

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