Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma

Fas is highly expressed on germinal center (GC) B cells, and mutations of FAS have been reported in diffuse large B cell lymphoma (DLBCL). Although GC-derived DLBCL has better overall outcomes than other DLBCL types, some cases are refractory, and the molecular basis for this is often unknown. We sh...

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Detalles Bibliográficos
Autores principales: Razzaghi, Raud, Agarwal, Shreya, Kotlov, Nikita, Plotnikova, Olga, Nomie, Krystle, Huang, Da Wei, Wright, George W., Smith, Grace A., Li, Moyi, Takata, Katsuyoshi, Yamadi, Maryam, Yao, Chen, O’Shea, John J., Phelan, James D., Pittaluga, Stefania, Scott, David W., Muppidi, Jagan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694576/
https://www.ncbi.nlm.nih.gov/pubmed/33237303
http://dx.doi.org/10.1084/jem.20201173

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