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ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging
Aging increases risk for ischemic vascular diseases. Bone marrow–derived hematopoietic stem/progenitor cells (HSPCs) are known to stimulate vascular regeneration. Activation of either the Mas receptor (MasR) by angiotensin-(1-7) (Ang-(1-7)) or angiotensin-converting enzyme-2 (ACE2) stimulates vasore...
Autores principales: | Joshi, S., Chittimalli, K., Jahan, J., Vasam, G., Jarajapu, Y. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694587/ https://www.ncbi.nlm.nih.gov/pubmed/33247425 http://dx.doi.org/10.1007/s11357-020-00306-w |
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