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Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity

The Notch signaling pathway governs cell-to-cell communication in higher eukaryotes. In Drosophila, after cleavage of the transmembrane receptor Notch, the intracellular domain of Notch (ICN) binds to the transducer Suppressor of Hairless (Su(H)) and shuttles into the nucleus to activate Notch targe...

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Detalles Bibliográficos
Autor principal: Maier, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694644/
https://www.ncbi.nlm.nih.gov/pubmed/33171957
http://dx.doi.org/10.3390/genes11111315