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Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity
The Notch signaling pathway governs cell-to-cell communication in higher eukaryotes. In Drosophila, after cleavage of the transmembrane receptor Notch, the intracellular domain of Notch (ICN) binds to the transducer Suppressor of Hairless (Su(H)) and shuttles into the nucleus to activate Notch targe...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694644/ https://www.ncbi.nlm.nih.gov/pubmed/33171957 http://dx.doi.org/10.3390/genes11111315 |