Cargando…

Ellagic Acid Prevents Dopamine Neuron Degeneration from Oxidative Stress and Neuroinflammation in MPTP Model of Parkinson’s Disease

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and is characterized by progressive dopaminergic neurodegeneration in the substantia nigra pars compacta area. In the present study, treatment of EA for 1 week at a dose of 10 mg/kg body weight prior to MPTP (25 mg/kg body...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ardah, Mustafa T., Bharathan, Greeshma, Kitada, Tohru, Haque, M. Emdadul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694688/ https://www.ncbi.nlm.nih.gov/pubmed/33172035 http://dx.doi.org/10.3390/biom10111519

Ejemplares similares

Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
por: Ardah, Mustafa T, et al.
Publicado: (2021)

Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease
por: Chung, Young C, et al.
Publicado: (2017)

Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease
por: Kim, Kyung In, et al.
Publicado: (2018)

Parkin Precipitates on Mitochondria via Aggregation and Autoubiquitination
por: Ardah, Mustafa T., et al.
Publicado: (2023)

Cholesterol contributes to dopamine-neuronal loss in MPTP mouse model of Parkinson’s disease: Involvement of mitochondrial dysfunctions and oxidative stress
por: Paul, Rajib, et al.
Publicado: (2017)

Eleven Crucial Pesticides Appear to Regulate Key Genes That Link MPTP Mechanism to Cause Parkinson’s Disease through the Selective Degeneration of Dopamine Neurons
por: Anirudhan, Athira, et al.
Publicado: (2023)

Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age
por: Costa, Giulia, et al.
Publicado: (2018)

Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
por: Koprich, James B, et al.
Publicado: (2008)

The phosphodiesterase inhibitor, ibudilast, attenuates neuroinflammation in the MPTP model of Parkinson’s disease
por: Schwenkgrub, Joanna, et al.
Publicado: (2017)

CNB-001 a Novel Curcumin Derivative, Guards Dopamine Neurons in MPTP Model of Parkinson's Disease
por: Jayaraj, Richard L., et al.
Publicado: (2014)

Trimethylamine N-Oxide Exacerbates Neuroinflammation and Motor Dysfunction in an Acute MPTP Mice Model of Parkinson’s Disease
por: Quan, Wei, et al.
Publicado: (2023)

Oxidative Stress and Neuroinflammation in Parkinson’s Disease: The Role of Dopamine Oxidation Products
por: Chakrabarti, Sasanka, et al.
Publicado: (2023)

Microglial cGAS drives neuroinflammation in the MPTP mouse models of Parkinson's disease
por: Ma, Chunmei, et al.
Publicado: (2023)

PEP-1-HO-1 prevents MPTP-induced degeneration of dopaminergic neurons in a Parkinson’s disease mouse model
por: Youn, Jong Kyu, et al.
Publicado: (2014)

MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson's Disease
por: Chung, Young Cheul, et al.
Publicado: (2013)

Silencing of Glucocerebrosidase Gene in Drosophila Enhances the Aggregation of Parkinson's Disease Associated α-Synuclein Mutant A53T and Affects Locomotor Activity
por: Abul Khair, Salema B., et al.
Publicado: (2018)

“Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson’s disease”
por: Rodríguez-Cruz, Alfredo, et al.
Publicado: (2019)

Coriandrum sativum attenuates microglia mediated neuroinflammation and MPTP-induced behavioral and oxidative changes in Parkinson’s disease mouse model
por: Koppula, Sushruta, et al.
Publicado: (2021)

Cannabinoid Type 2 (CB(2)) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinson's Disease
por: Javed, Hayate, et al.
Publicado: (2016)

Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age
por: Costa, Giulia, et al.
Publicado: (2019)

Chronic behavioral stress exaggerates motor deficit and neuroinflammation in the MPTP mouse model of Parkinson's disease
por: Lauretti, E, et al.
Publicado: (2016)

Botulinum Toxin A Ameliorates Neuroinflammation in the MPTP and 6-OHDA-Induced Parkinson’s Disease Models
por: Ham, Hyeon Joo, et al.
Publicado: (2022)

Lactulose and Melibiose Attenuate MPTP-Induced Parkinson’s Disease in Mice by Inhibition of Oxidative Stress, Reduction of Neuroinflammation and Up-Regulation of Autophagy
por: Lin, Chih-Hsin, et al.
Publicado: (2020)

Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson’s Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment
por: Atiq, Abubakar, et al.
Publicado: (2023)

The Association of Iron and the Pathologies of Parkinson’s Diseases in MPTP/MPP(+)-Induced Neuronal Degeneration in Non-human Primates and in Cell Culture
por: Shi, Liangqin, et al.
Publicado: (2019)

Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia
por: He, Xue-mei, et al.
Publicado: (2020)

Lycium barbarum polysaccharide improves dopamine metabolism and symptoms in an MPTP-induced model of Parkinson’s disease
por: Song, Jiangbo, et al.
Publicado: (2022)

Ellagic Acid Protects the Brain Against 6-Hydroxydopamine Induced Neuroinflammation in a Rat Model of Parkinson’s Disease
por: Farbood, Yaghoob, et al.
Publicado: (2015)

ATP13A2 Gene Silencing in Drosophila Affects Autophagic Degradation of A53T Mutant α-Synuclein
por: Dhanushkodi, Nisha R., et al.
Publicado: (2023)

MicroRNA-30e regulates neuroinflammation in MPTP model of Parkinson’s disease by targeting Nlrp3
por: Li, Dongsheng, et al.
Publicado: (2017)

Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone
por: Javed, Hayate, et al.
Publicado: (2016)

Isradipine attenuates MPTP-induced dopamine neuron degeneration by inhibiting up-regulation of L-type calcium channels and iron accumulation in the substantia nigra of mice
por: Wang, Qi-Min, et al.
Publicado: (2017)

Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion
por: Boggia, Raffaella, et al.
Publicado: (2020)

25-Hydroxyvitamin D Depletion Does Not Exacerbate MPTP-Induced Dopamine Neuron Damage in Mice
por: Dean, E. Danielle, et al.
Publicado: (2012)

Transgenic supplementation of SIRT1 fails to alleviate acute loss of nigrostriatal dopamine neurons and gliosis in a mouse model of MPTP-induced parkinsonism
por: Kitao, Yasuko, et al.
Publicado: (2015)

Neutral Sphingomyelinase Behaviour in Hippocampus Neuroinflammation of MPTP-Induced Mouse Model of Parkinson's Disease and in Embryonic Hippocampal Cells
por: Cataldi, Samuela, et al.
Publicado: (2017)

RIPK1 Regulates Microglial Activation in Lipopolysaccharide-Induced Neuroinflammation and MPTP-Induced Parkinson’s Disease Mouse Models
por: Kim, Do-Yeon, et al.
Publicado: (2023)

Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons
por: Bayliss, Jacqueline A., et al.
Publicado: (2016)

Herbal medicine (Hepad) prevents dopaminergic neuronal death in the rat MPTP model of Parkinson’s disease
por: Kim, Dong Hee, et al.
Publicado: (2019)

Dilated Perivascular Space in the Midbrain May Reflect Dopamine Neuronal Degeneration in Parkinson’s Disease
por: Li, Yanxuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9a0ce7j30u5bi7056tq43l4p60