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Polymeric Drug Delivery Systems Bearing Cholesterol Moieties: A Review

This review aims to provide an overview of polymers comprising cholesterol moiety/ies designed to be used in drug delivery. Over the last two decades, there have been many papers published in this field, which are summarized in this review. The primary focus of this article is on the methods of synt...

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Detalles Bibliográficos
Autores principales: Misiak, Paweł, Markiewicz, Karolina H., Szymczuk, Dawid, Wilczewska, Agnieszka Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694753/
https://www.ncbi.nlm.nih.gov/pubmed/33172152
http://dx.doi.org/10.3390/polym12112620
Descripción
Sumario:This review aims to provide an overview of polymers comprising cholesterol moiety/ies designed to be used in drug delivery. Over the last two decades, there have been many papers published in this field, which are summarized in this review. The primary focus of this article is on the methods of synthesis of polymers bearing cholesterol in the main chain or as side chains. The data related to the composition, molecular weight, and molecular weight distribution of polymers are presented. Moreover, other aspects, such as forms of carriers, types of encapsulated drugs, encapsulation efficiency and capacity, are also included.