Cargando…

Autophagy Genes for Wet Age-Related Macular Degeneration in a Finnish Case-Control Study

Age-related macular degeneration is an eye disease that is the main cause of legal blindness in the elderly in developed countries. Despite this, its pathogenesis is not completely known, and many genetic, epigenetic, environmental and lifestyle factors may be involved. Vision loss in age-related ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paterno, Jussi J., Koskela, Ali, Hyttinen, Juha M.T., Vattulainen, Elina, Synowiec, Ewelina, Tuuminen, Raimo, Watala, Cezary, Blasiak, Janusz, Kaarniranta, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694766/ https://www.ncbi.nlm.nih.gov/pubmed/33172148 http://dx.doi.org/10.3390/genes11111318

Ejemplares similares

Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
por: Kaarniranta, Kai, et al.
Publicado: (2016)

Expression of VEGFA‐regulating miRNAs and mortality in wet AMD
por: Blasiak, Janusz, et al.
Publicado: (2019)

Genetic Variability in DNA Repair Proteins in Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2012)

Non-Coding RNAs Regulating Mitochondrial Functions and the Oxidative Stress Response as Putative Targets against Age-Related Macular Degeneration (AMD)
por: Hyttinen, Juha M. T., et al.
Publicado: (2023)

Inflammation and its role in age-related macular degeneration
por: Kauppinen, Anu, et al.
Publicado: (2016)

Potential of Long Non-Coding RNAs in Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2021)

Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α(-/-) Mouse Model
por: Sridevi Gurubaran, Iswariyaraja, et al.
Publicado: (2020)

Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2023)

Zinc and Autophagy in Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2020)

Dietary Polyphenols in Age-Related Macular Degeneration: Protection against Oxidative Stress and Beyond
por: Pawlowska, Elzbieta, et al.
Publicado: (2019)

Long-term effects of intravitreal bevacizumab and aflibercept on intraocular pressure in wet age-related macular degeneration
por: Kähkönen, Mikael, et al.
Publicado: (2021)

Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1α (-/-) Mouse Model Evoke Complement Component C5a Independent of C3
por: Sridevi Gurubaran, Iswariyaraja, et al.
Publicado: (2021)

Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration
por: Synowiec, Ewelina, et al.
Publicado: (2012)

Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2016)

Anatomical and functional response after conversion to aflibercept using the treat-and-extend regimen protocol in bevacizumab treatment-resistant wet age-related macular degeneration
por: Taipale, Claudia, et al.
Publicado: (2018)

Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2013)

Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)
por: Tokarz, Paulina, et al.
Publicado: (2013)

Oxidative Stress, Hypoxia, and Autophagy in the Neovascular Processes of Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2014)

Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration
por: Blasiak, Janusz, et al.
Publicado: (2019)

Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD)
por: Kaarniranta, Kai, et al.
Publicado: (2019)

DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation
por: Kaarniranta, Kai, et al.
Publicado: (2020)

An association between polymorphism of the heme oxygenase-1 and -2 genes and age-related macular degeneration
por: Synowiec, Ewelina, et al.
Publicado: (2011)

Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration
por: Kaarniranta, Kai, et al.
Publicado: (2020)

The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology
por: Hyttinen, Juha M. T., et al.
Publicado: (2019)

Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
por: Blasiak, Janusz, et al.
Publicado: (2017)

Lack of association between the c.544G>A polymorphism of the heme oxygenase-2 gene and age-related macular degeneration
por: Wysokinski, Daniel, et al.
Publicado: (2011)

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
por: Felszeghy, Szabolcs, et al.
Publicado: (2018)

Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α
por: Blasiak, Janusz, et al.
Publicado: (2021)

Effect of cataract surgery on quality of life for patients with severe vision impairment due to age-related macular degeneration
por: Taipale, Claudia, et al.
Publicado: (2020)

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
por: Kaarniranta, Kai, et al.
Publicado: (2013)

Intravitreal bevacizumab injections versus dexamethasone implant for treatment-naïve retinal vein occlusion related macular edema
por: Laine, Ilkka, et al.
Publicado: (2017)

Imaging of Wet Age-Related Macular Degeneration
por: Kenan, Damer
Publicado: (2016)

The Role of Mitochondrial DNA Damage and Repair in the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors
por: Glowacki, Sylwester, et al.
Publicado: (2013)

Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells
por: Koskela, Ali, et al.
Publicado: (2014)

Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice
por: Blasiak, Janusz, et al.
Publicado: (2021)

Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice
por: Tamminen, Toni, et al.
Publicado: (2021)

2-Hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation
por: Szczepanska, Joanna, et al.
Publicado: (2011)

Pegaptanib in the treatment of wet, age-related macular degeneration
por: Vinores, Stanley A
Publicado: (2006)

Bevasiranib for the Treatment of Wet, Age-Related Macular Degeneration
por: Garba, Adinoyi O., et al.
Publicado: (2010)

Microcurrent stimulation in the treatment of dry and wet macular degeneration
por: Chaikin, Laurie, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_987fbhsg5huv9p1gvk7m9skn6r