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A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty

Background: As much as there are unmet needs for brief frailty assessment in patients with chronic obstructive pulmonary disease (COPD), the lack of a simplified and comprehensive dyspnea evaluation system that focuses on the patients’ perceptions of dyspnea and their COPD living disabilities remain...

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Autores principales: Oishi, Keiji, Matsunaga, Kazuto, Harada, Misa, Suizu, Junki, Murakawa, Keita, Chikumoto, Ayumi, Ohteru, Yuichi, Matsuda, Kazuki, Uehara, Sho, Hamada, Kazuki, Ohata, Shuichiro, Murata, Yoriyuki, Yamaji, Yoshikazu, Asami-Noyama, Maki, Edakuni, Nobutaka, Kakugawa, Tomoyuki, Hirano, Tsunahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694778/
https://www.ncbi.nlm.nih.gov/pubmed/33172080
http://dx.doi.org/10.3390/jcm9113580
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author Oishi, Keiji
Matsunaga, Kazuto
Harada, Misa
Suizu, Junki
Murakawa, Keita
Chikumoto, Ayumi
Ohteru, Yuichi
Matsuda, Kazuki
Uehara, Sho
Hamada, Kazuki
Ohata, Shuichiro
Murata, Yoriyuki
Yamaji, Yoshikazu
Asami-Noyama, Maki
Edakuni, Nobutaka
Kakugawa, Tomoyuki
Hirano, Tsunahiko
author_facet Oishi, Keiji
Matsunaga, Kazuto
Harada, Misa
Suizu, Junki
Murakawa, Keita
Chikumoto, Ayumi
Ohteru, Yuichi
Matsuda, Kazuki
Uehara, Sho
Hamada, Kazuki
Ohata, Shuichiro
Murata, Yoriyuki
Yamaji, Yoshikazu
Asami-Noyama, Maki
Edakuni, Nobutaka
Kakugawa, Tomoyuki
Hirano, Tsunahiko
author_sort Oishi, Keiji
collection PubMed
description Background: As much as there are unmet needs for brief frailty assessment in patients with chronic obstructive pulmonary disease (COPD), the lack of a simplified and comprehensive dyspnea evaluation system that focuses on the patients’ perceptions of dyspnea and their COPD living disabilities remains a major challenge. We developed patient-reported outcome measures for dyspnea-related behavior and activity limitation (PROMs-D), which consisted of the Activity-limit Dyspnea Scale (ADS) and Self-Limit Dyspnea Scale (SDS), while investigated the usefulness of PROMs-D in identifying frailty. Methods: We administered PROMs-D and frailty status evaluations in 128 outpatients. Results: We classified 30 (23.4%), 50 (39.0%), and 48 (37.5%) patients as robust, prefrail, and frail, respectively. There was a positive correlation between SDS and ADS (ρ = 0.67, p < 0.001), and both ADS and SDS had high accuracies for detecting frailty (AUC, 0.82 and 0.78, respectively). Moreover, a PROMs-D score that consisted of the sum of ADS and SDS was more effective in stratifying frailty (cutoff value, 2; AUC, 0.85; sensitivity, 60%; specificity, 95%). Conclusions: PROMs-D could be used as the first step for frailty screening in patients with COPD, and we propose the importance of capturing the troublesome nature of living behaviors due to dyspnea in daily clinical practice.
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spelling pubmed-76947782020-11-28 A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty Oishi, Keiji Matsunaga, Kazuto Harada, Misa Suizu, Junki Murakawa, Keita Chikumoto, Ayumi Ohteru, Yuichi Matsuda, Kazuki Uehara, Sho Hamada, Kazuki Ohata, Shuichiro Murata, Yoriyuki Yamaji, Yoshikazu Asami-Noyama, Maki Edakuni, Nobutaka Kakugawa, Tomoyuki Hirano, Tsunahiko J Clin Med Article Background: As much as there are unmet needs for brief frailty assessment in patients with chronic obstructive pulmonary disease (COPD), the lack of a simplified and comprehensive dyspnea evaluation system that focuses on the patients’ perceptions of dyspnea and their COPD living disabilities remains a major challenge. We developed patient-reported outcome measures for dyspnea-related behavior and activity limitation (PROMs-D), which consisted of the Activity-limit Dyspnea Scale (ADS) and Self-Limit Dyspnea Scale (SDS), while investigated the usefulness of PROMs-D in identifying frailty. Methods: We administered PROMs-D and frailty status evaluations in 128 outpatients. Results: We classified 30 (23.4%), 50 (39.0%), and 48 (37.5%) patients as robust, prefrail, and frail, respectively. There was a positive correlation between SDS and ADS (ρ = 0.67, p < 0.001), and both ADS and SDS had high accuracies for detecting frailty (AUC, 0.82 and 0.78, respectively). Moreover, a PROMs-D score that consisted of the sum of ADS and SDS was more effective in stratifying frailty (cutoff value, 2; AUC, 0.85; sensitivity, 60%; specificity, 95%). Conclusions: PROMs-D could be used as the first step for frailty screening in patients with COPD, and we propose the importance of capturing the troublesome nature of living behaviors due to dyspnea in daily clinical practice. MDPI 2020-11-06 /pmc/articles/PMC7694778/ /pubmed/33172080 http://dx.doi.org/10.3390/jcm9113580 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oishi, Keiji
Matsunaga, Kazuto
Harada, Misa
Suizu, Junki
Murakawa, Keita
Chikumoto, Ayumi
Ohteru, Yuichi
Matsuda, Kazuki
Uehara, Sho
Hamada, Kazuki
Ohata, Shuichiro
Murata, Yoriyuki
Yamaji, Yoshikazu
Asami-Noyama, Maki
Edakuni, Nobutaka
Kakugawa, Tomoyuki
Hirano, Tsunahiko
A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
title A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
title_full A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
title_fullStr A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
title_full_unstemmed A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
title_short A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
title_sort new dyspnea evaluation system focusing on patients’ perceptions of dyspnea and their living disabilities: the linkage between copd and frailty
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694778/
https://www.ncbi.nlm.nih.gov/pubmed/33172080
http://dx.doi.org/10.3390/jcm9113580
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