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Effects of administration of ascorbic acid and low‐dose hydrocortisone after infusion of sublethal doses of lipopolysaccharide to horses

BACKGROUND: Sepsis is associated with ascorbic acid (AA) depletion and critical illness‐related corticosteroid insufficiency (CIRCI) in humans. HYPOTHESES: Intravenous infusion of lipopolysaccharide (LPS) would (a) decrease endogneous AA concentrations, (b) induce CIRCI and (c) administration of a c...

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Detalles Bibliográficos
Autores principales: Anderson, Melinda J., Ibrahim, Alina S., Cooper, Bruce R., Woolcock, Andrew D., Moore, George E., Taylor, Sandra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694830/
https://www.ncbi.nlm.nih.gov/pubmed/33026127
http://dx.doi.org/10.1111/jvim.15896