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Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom

BACKGROUND: Little epidemiological evaluation of recurrent seizure disorders in cats currently exists in veterinary literature. OBJECTIVES: To report the prevalence and risk factors for recurrent seizure disorders (RSD) and epilepsy in cats presented to primary care veterinary practices in the Unite...

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Autores principales: O'Neill, Dan Gerard, Phillipps, Stephanie A., Egan, Jordon R., Brodbelt, David, Church, David B., Volk, Holger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694832/
https://www.ncbi.nlm.nih.gov/pubmed/32974979
http://dx.doi.org/10.1111/jvim.15881
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author O'Neill, Dan Gerard
Phillipps, Stephanie A.
Egan, Jordon R.
Brodbelt, David
Church, David B.
Volk, Holger A.
author_facet O'Neill, Dan Gerard
Phillipps, Stephanie A.
Egan, Jordon R.
Brodbelt, David
Church, David B.
Volk, Holger A.
author_sort O'Neill, Dan Gerard
collection PubMed
description BACKGROUND: Little epidemiological evaluation of recurrent seizure disorders in cats currently exists in veterinary literature. OBJECTIVES: To report the prevalence and risk factors for recurrent seizure disorders (RSD) and epilepsy in cats presented to primary care veterinary practices in the United Kingdom (UK). ANIMALS: A total of 285 547 cats under veterinary care during 2013 presenting to 282 primary care clinics in the UK. METHODS: Cohort study using multivariable logistic regression modeling for risk factor analysis. RESULTS: There were 458 confirmed RSD cases, giving a 1‐year period prevalence of 0.16% (95% confidence interval [CI], 0.15‐0.18). A subset of 114 (24.89%) cases was recorded as having epilepsy, giving a 1‐year period prevalence of 0.04% (95% CI, 0.03‐0.5). Increasing age was significantly associated with increasing odds of RSD. Breed, sex, neuter status, and body weight were not associated with RSD. Epilepsy was most frequently diagnosed in adult to middle‐aged cats. Cats aged 3.0 to <6.0 years had 3.32 times higher odds of epilepsy diagnosis compared to cats <3.0 years of age. Insured cats were more likely to be diagnosed with epilepsy compared to noninsured cats. CONCLUSIONS AND CLINICAL IMPORTANCE: Although less common than in dogs, RSD and epilepsy still comprise an important disorder group in the UK cat population. Aging is a significant risk factor for these disorders in cats.
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spelling pubmed-76948322020-12-07 Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom O'Neill, Dan Gerard Phillipps, Stephanie A. Egan, Jordon R. Brodbelt, David Church, David B. Volk, Holger A. J Vet Intern Med SMALL ANIMAL BACKGROUND: Little epidemiological evaluation of recurrent seizure disorders in cats currently exists in veterinary literature. OBJECTIVES: To report the prevalence and risk factors for recurrent seizure disorders (RSD) and epilepsy in cats presented to primary care veterinary practices in the United Kingdom (UK). ANIMALS: A total of 285 547 cats under veterinary care during 2013 presenting to 282 primary care clinics in the UK. METHODS: Cohort study using multivariable logistic regression modeling for risk factor analysis. RESULTS: There were 458 confirmed RSD cases, giving a 1‐year period prevalence of 0.16% (95% confidence interval [CI], 0.15‐0.18). A subset of 114 (24.89%) cases was recorded as having epilepsy, giving a 1‐year period prevalence of 0.04% (95% CI, 0.03‐0.5). Increasing age was significantly associated with increasing odds of RSD. Breed, sex, neuter status, and body weight were not associated with RSD. Epilepsy was most frequently diagnosed in adult to middle‐aged cats. Cats aged 3.0 to <6.0 years had 3.32 times higher odds of epilepsy diagnosis compared to cats <3.0 years of age. Insured cats were more likely to be diagnosed with epilepsy compared to noninsured cats. CONCLUSIONS AND CLINICAL IMPORTANCE: Although less common than in dogs, RSD and epilepsy still comprise an important disorder group in the UK cat population. Aging is a significant risk factor for these disorders in cats. John Wiley & Sons, Inc. 2020-09-25 2020 /pmc/articles/PMC7694832/ /pubmed/32974979 http://dx.doi.org/10.1111/jvim.15881 Text en © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle SMALL ANIMAL
O'Neill, Dan Gerard
Phillipps, Stephanie A.
Egan, Jordon R.
Brodbelt, David
Church, David B.
Volk, Holger A.
Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
title Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
title_full Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
title_fullStr Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
title_full_unstemmed Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
title_short Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
title_sort epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the united kingdom
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694832/
https://www.ncbi.nlm.nih.gov/pubmed/32974979
http://dx.doi.org/10.1111/jvim.15881
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