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Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs

BACKGROUND: Systemic hypertension (SH) is a persistent and pathological increase in arterial blood pressure (BP). Chronic SH leads to an increase in aortic (Ao) stiffness, and measuring Ao elasticity is useful for estimating Ao stiffness in humans. Currently, no literature in veterinary medicine des...

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Autores principales: Corda, Andrea, Corda, Francesca, Caivano, Domenico, Saderi, Laura, Sotgiu, Giovanni, Mollica, Alessandra, Birettoni, Francesco, Porciello, Francesco, Pinna Parpaglia, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694867/
https://www.ncbi.nlm.nih.gov/pubmed/32949191
http://dx.doi.org/10.1111/jvim.15891
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author Corda, Andrea
Corda, Francesca
Caivano, Domenico
Saderi, Laura
Sotgiu, Giovanni
Mollica, Alessandra
Birettoni, Francesco
Porciello, Francesco
Pinna Parpaglia, Maria Luisa
author_facet Corda, Andrea
Corda, Francesca
Caivano, Domenico
Saderi, Laura
Sotgiu, Giovanni
Mollica, Alessandra
Birettoni, Francesco
Porciello, Francesco
Pinna Parpaglia, Maria Luisa
author_sort Corda, Andrea
collection PubMed
description BACKGROUND: Systemic hypertension (SH) is a persistent and pathological increase in arterial blood pressure (BP). Chronic SH leads to an increase in aortic (Ao) stiffness, and measuring Ao elasticity is useful for estimating Ao stiffness in humans. Currently, no literature in veterinary medicine describes noninvasive assessment of abdominal Ao elasticity in dogs with SH. OBJECTIVE: Compare ultrasonographic‐derived abdominal Ao strain (AoSt) between hypertensive (HT) and normotensive (NT) dogs. ANIMALS: Fifty privately‐owned dogs with clinical signs, conditions, or both potentially associated with SH. METHODS: Prospective observational case‐control study. Aortic stiffness was estimated by calculating AoSt as follows: AoSt = ([AoDs − AoDd]/AoDd) × 100, where AoDs and AoDd are the Ao diameter in systole and in diastole, respectively. Aortic stiffness was calculated from 2 different Ao transverse sections, the first caudal to the left renal artery (K_AoSt), and the second cranial to the external iliac arteries (I_AoSt). RESULTS: Thirty‐two dogs were included in the HT group and 18 in the NT group. Both K_AoSt and I_AoSt in HT dogs were significantly lower (P < .05) than in NT dogs (7.4 ± SD 3.6) vs 10.3 (±3.8) and 5.7 (interquartile range [IQR], 3.9‐7.5) vs 8.1 (IQR, 7‐10.3), respectively. Only K_AoSt was significantly influenced by age. CONCLUSIONS AND CLINICAL IMPORTANCE: Ultrasonographic Ao elasticity assessment was feasible to compare HT and NT dogs. Results indicated that K_AoSt and I_AoSt indices can be used to assess SH‐related Ao stiffness, especially when indirect BP measurements are inconsistent or inaccurate. Additional studies to assess the AoSt in healthy dogs of various ages are needed.
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spelling pubmed-76948672020-12-07 Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs Corda, Andrea Corda, Francesca Caivano, Domenico Saderi, Laura Sotgiu, Giovanni Mollica, Alessandra Birettoni, Francesco Porciello, Francesco Pinna Parpaglia, Maria Luisa J Vet Intern Med SMALL ANIMAL BACKGROUND: Systemic hypertension (SH) is a persistent and pathological increase in arterial blood pressure (BP). Chronic SH leads to an increase in aortic (Ao) stiffness, and measuring Ao elasticity is useful for estimating Ao stiffness in humans. Currently, no literature in veterinary medicine describes noninvasive assessment of abdominal Ao elasticity in dogs with SH. OBJECTIVE: Compare ultrasonographic‐derived abdominal Ao strain (AoSt) between hypertensive (HT) and normotensive (NT) dogs. ANIMALS: Fifty privately‐owned dogs with clinical signs, conditions, or both potentially associated with SH. METHODS: Prospective observational case‐control study. Aortic stiffness was estimated by calculating AoSt as follows: AoSt = ([AoDs − AoDd]/AoDd) × 100, where AoDs and AoDd are the Ao diameter in systole and in diastole, respectively. Aortic stiffness was calculated from 2 different Ao transverse sections, the first caudal to the left renal artery (K_AoSt), and the second cranial to the external iliac arteries (I_AoSt). RESULTS: Thirty‐two dogs were included in the HT group and 18 in the NT group. Both K_AoSt and I_AoSt in HT dogs were significantly lower (P < .05) than in NT dogs (7.4 ± SD 3.6) vs 10.3 (±3.8) and 5.7 (interquartile range [IQR], 3.9‐7.5) vs 8.1 (IQR, 7‐10.3), respectively. Only K_AoSt was significantly influenced by age. CONCLUSIONS AND CLINICAL IMPORTANCE: Ultrasonographic Ao elasticity assessment was feasible to compare HT and NT dogs. Results indicated that K_AoSt and I_AoSt indices can be used to assess SH‐related Ao stiffness, especially when indirect BP measurements are inconsistent or inaccurate. Additional studies to assess the AoSt in healthy dogs of various ages are needed. John Wiley & Sons, Inc. 2020-09-19 2020 /pmc/articles/PMC7694867/ /pubmed/32949191 http://dx.doi.org/10.1111/jvim.15891 Text en © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle SMALL ANIMAL
Corda, Andrea
Corda, Francesca
Caivano, Domenico
Saderi, Laura
Sotgiu, Giovanni
Mollica, Alessandra
Birettoni, Francesco
Porciello, Francesco
Pinna Parpaglia, Maria Luisa
Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
title Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
title_full Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
title_fullStr Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
title_full_unstemmed Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
title_short Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
title_sort ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694867/
https://www.ncbi.nlm.nih.gov/pubmed/32949191
http://dx.doi.org/10.1111/jvim.15891
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