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Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy

BACKGROUND: T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 cells (resulting in so called ex-Th17 cells). Thus, a strict separation between the two T cell subsets in the con...

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Detalles Bibliográficos
Autores principales: Loos, Julia, Schmaul, Samantha, Noll, Theresa Marie, Paterka, Magdalena, Schillner, Miriam, Löffel, Julian T., Zipp, Frauke, Bittner, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694901/
https://www.ncbi.nlm.nih.gov/pubmed/33243290
http://dx.doi.org/10.1186/s12974-020-02021-x